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Unfortunately, the antibody (ID:156030) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



TLR4

toll-like receptor 4

Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni2+. Responses triggered by Ni2+ require non-conserved histidines and are, therefore, species-specific. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to CD36. This event induces the formation of a heterodimer of TLR4 and TLR6, which is rapidly internalized and triggers inflammatory response, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion.

Gene Name: toll-like receptor 4
Family/Subfamily: Toll-like Receptor , not assigned-Toll-like Receptor
Synonyms: TLR4, CD284, CD284 antigen, Homolog of Drosophila toll, TLR-4, TOLL, ARMD10, Toll-like receptor 4, HToll
Target Sequences: NM_138554 O00206 O00206

Publications (2)

1
High-mobility group box 1 activates integrin-dependent homing of endothelial progenitor cells. Chavakis E, Hain A, Vinci M, Carmona G, Bianchi ME, Vajkoczy P, Zeiher AM, Chavakis T, Dimmeler S. Circulation research. 2007 100:204-12. [PubMed:17218606] Related Antibodies: LS-C40824.
2
Tissue expression of Toll-like receptors 2 and 4 in sporadic human colorectal cancer. Nihon-Yanagi Y, Terai K, Murano T, Matsumoto T, Okazumi S. Cancer immunology, immunotherapy : CII. 2013 Jan;61:71-7. [Full Text Article] [PubMed:21845432] [PMC:PMC3249192] Related Antibodies: LS-B2070.

Filtered By: None
Target
tlr4 (194)
Reactivity
Human (161)
Mouse (71)
Rat (36)
Baboon (1)
Bovine (2)
Chimpanzee (6)
Dog (16)
Gibbon (3)
Guinea pig (9)
Hamster (2)
Horse (1)
Macaque (2)
Monkey (11)
Orangutan (3)
Pig (12)
Rhesus monkey (5)
Application
IHC (93)
IHC-Fr (5)
IHC-P (51)
WB (130)
Flo (88)
Block (1)
ELISA (32)
Func (8)
ICC (34)
IF (14)
IP (30)
Neut (5)
Peptide-ELISA (1)
Host
rabbit (127)
mouse (60)
goat (2)
rat (5)
Isotype
IgG (66)
IgG1 (3)
IgG2a (34)
IgG2a,k (13)
IgG2b (2)
IgG2b,k (5)
Clonality
monoclonal mc (65)
polyclonal pc (129)
Clone
11E372 (1)
1E11 (1)
3B6 (1)
3C3 (3)
76B357.1 (2)
ABM19C4 (1)
HTA125 (24)
HTA125, Biotinylated (1)
TLR4/230 (2)
UT49 (2)
Format
AF488 Conjugated (1)
AF647 Conjugated (1)
AP Conjugated (6)
APC (4)
APC Conjugated (11)
Atto 390 Conjugated (1)
Atto 488 Conjugated (1)
Atto 565 Conjugated (1)
Atto 594 Conjugated (2)
Atto 633 Conjugated (1)
Atto 655 Conjugated (1)
Atto 680 Conjugated (1)
Atto 700 Conjugated (1)
Azide-free (7)
Biotin Conjugated (22)
Cy3 Conjugated (4)
Cy7 Conjugated (5)
DY488 Conjugated (2)
DY550 Conjugated (2)
DY650 Conjugated (2)
FITC Conjugated (23)
HRP Conjugated (11)
Low Endotoxin (2)
PE (2)
PE Conjugated (15)
PerCP Conjugated (1)
RPE Conjugated (3)
SA Conjugated (1)
Unconjugated (75)
Epitope
aa420-435 (19)
Internal (16)
aa326-634 (9)
aa25-55 (8)
aa26-269 (8)
aa49-247 (8)
aa669-698 (8)
C-Terminus (6)
aa100-200 (4)
aa260-309 (4)
N-Terminus (2)
aa161-192 (2)
aa418-435 (2)
aa650-700 (2)
aa100-150 (1)
aa39-56 (1)
aa392-441 (1)
aa400-450 (1)
aa421-470 (1)
aa45-320 (1)
aa6-169 (1)
aa819 (1)
Publications
No (192)
Yes (2)
Showing 1-25 out of 194 results
TLR4 Antibody (Internal) IHC-plus™ LS-A9704
Anti-TLR4 antibody LS-A9704 IHC of human placenta, decidua. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Rabbit Polyclonal to Human TLR4
Human
IHC IHC-P
Unconjugated
TLR4 Antibody (aa100-200, clone 76B357.1) IHC-plus™ LS-B2070
Anti-TLR4 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2070 concentration 5 ug/ml.
Western blot of TLR4 using antibody at 2 ug/ml on (A) human intestine and 6 ug/ml on (B) mouse intestine and C) rat intestine lysate.

Mouse Monoclonal [clone 76B357.1] (IgG2b,k) to Human TLR4
Mouse, Rat, Human
Flo IHC IHC-P WB
Unconjugated
TLR4 Antibody (clone 1E11) IHC-plus™ LS-B2254
Anti-TLR4 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2254 concentration 5 ug/ml.

Mouse Monoclonal [clone 1E11] (IgG2a) to Human TLR4
Human
ELISA Flo IHC IHC-P
Unconjugated
TLR4 Antibody (clone HTA125) LS-C40824
Human peripheral blood monocytes stained with HTA125 PE

Mouse Monoclonal [clone HTA125] (IgG2a) to Human TLR4
Guinea pig, Pig, Human
Flo IF IHC IHC-Fr
Unconjugated
TLR4 Antibody (C-Terminus) IHC-plus™ LS-B4696
Anti-TLR4 antibody IHC of human neutrophils. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4696 concentration 5 ug/ml.
Anti-TLR4 antibody IHC of human neutrophils. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4696 concentration 5 ug/ml.

Rabbit Polyclonal (IgG) to Human TLR4
Human
IHC IHC-P
Unconjugated
TLR4 Antibody LS-C44226

Mouse Monoclonal (IgG2a) to Human TLR4
Dog, Guinea pig, Pig, Rhesus monkey, Human
Flo IP WB
Unconjugated
TLR4 Antibody (FITC) LS-C44225

Mouse Monoclonal (IgG2a) to Human TLR4
Dog, Guinea pig, Pig, Rhesus monkey, Human
Flo IP WB
FITC Conjugated
TLR4 Antibody (clone HTA125, PE, Cy7) LS-C107190
Staining of human TLR4-transfected cells with PE-Cy7 Mouse IgG2a, K isotype control (open histogram) or PE-Cy7 anti-human TLR4 (HTA125) (colored histogram). Total viable cells were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Mouse Monoclonal [clone HTA125] (IgG2a,k) to Human TLR4
Human
Flo
PE, Cy7 Conjugated
TLR4 Antibody LS-C180173
Immunohistochemistry: TLR4 Antibody - Analysis of TLR4 in mouse smooth muscle using DAB with hematoxylin counterstain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Immunohistochemistry: TLR4 Antibody - Analysis of TLR4 in mouse spleen using DAB with hematoxylin counterstain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal to Human TLR4
Mouse, Rat, Human
ICC IHC IHC-P WB
Unconjugated
TLR4 Antibody (clone HTA125) LS-C546
Flow cytometry of TLR4 using antibody on PBMCs at 2 ug/ 1X10^6 cells. M1 gate are unstained PBMC.

Mouse Monoclonal [clone HTA125] (IgG2a) to Human TLR4
Human
Flo ICC IP Neut
Unconjugated
TLR4 Antibody (aa418-435) LS-C756
Western blot of TLR4 using antibody at 2 ug/ml on partial recombinant mouse TLR4 protein.

Rabbit Polyclonal (IgG) to Human TLR4
Mouse, Human, Monkey
ICC IHC IHC-Fr WB
Unconjugated
TLR4 Antibody (aa650-700) IHC-plus™ LS-B8675
Anti-TLR4 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8675 dilution 5 ug/ml.
Western blot of TLR4 in human intestine lysate in the 1) absence and 2) presence of immunizing peptide using TLR4 antibody at 0.1 ug/ml. Goat anti-rabbit Ig HRP secondary antibody, and PicoTect ECL substrate solution, were used for this test.

Rabbit Polyclonal to Human TLR4
Bovine, Horse, Macaque, Human
IHC IHC-P WB
Unconjugated
TLR4 Antibody (aa100-200, FITC) LS-C90574

Mouse Monoclonal (IgG2b,k) to Human TLR4
Mouse, Rat, Hamster, Human
Flo
FITC Conjugated
TLR4 Antibody (aa25-55) LS-C98273
Western blot of anti-mTLR4 antibody in mouse spleen cell lysate. mTLR4 (arrow) was detected using purified antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.

Rabbit Polyclonal to Mouse TLR4
Mouse
IHC WB
Unconjugated
TLR4 Antibody (aa161-192) LS-C187853
Immunohistochemistry of paraffin-embeddedi human tonsil stained with Goat anti-human CD284
Immunohistochemistry of paraffin-embeddedi mouse spleen stained with Goat anti-human CD284

Goat Polyclonal (IgG) to Human TLR4
Mouse, Human
IHC IHC-P WB
Unconjugated
TLR4 Antibody (aa100-200, clone 76B357.1, Azide-free) LS-C367232
Immunohistochemistry-Paraffin: TLR4 Antibody (76B357.1) [Azide Free] - Human skin stained with TLR4 antibody (5 ug/ml), peroxidase-conjugate and DAB chromogen. This image was taken for the unmodified form of this product. Other forms have not been tested.
Immunohistochemistry-Paraffin: TLR4 Antibody (76B357.1) [Azide Free] - Formalin-fixed, paraffin-embedded human testis tissue stained with TLR4 antibody (5 ug/ml). This image was taken for the unmodified form of this product. Other forms have not been tested.

Mouse Monoclonal [clone 76B357.1] (IgG2b,k) to Human TLR4
Mouse, Rat, Human
Flo ICC IF IHC IHC-P WB
Unconjugated, Azide-free
TLR4 Antibody (clone 3B6) IHC-plus™ LS-B6066
Anti-TLR4 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6066 concentration 5 ug/ml.

Mouse Monoclonal [clone 3B6] (IgG2a,k) to Human TLR4
Human
ELISA IHC IHC-P WB
Unconjugated
TLR4 Antibody (aa100-150) LS-C845
Western blot of TLR4 using antibody on (A) 0.1 ug/lane recombinant mouse TLR4 protein (tested at 2 ug/ml), (B) 20 ug/lane human intestine, and (C) 20 ug/lane mouse intestine (tested at 5 ug/ml on intestine lysates).

Rabbit Polyclonal (IgG) to Human TLR4
Mouse, Human
IP WB
Unconjugated
TLR4 Antibody (aa650-700) LS-C148471
Western blot of TLR4 in Daudi cell lysate in the 1) absence and 2) presence of immunizing peptide, 3) Ramos cell lysate, 4) human colon tumor lysate.

Rabbit Polyclonal to Human TLR4
Human, Monkey, Baboon, Macaque
WB
Unconjugated
TLR4 Antibody (clone TLR4/230) LS-C391056

Mouse Monoclonal [clone TLR4/230] (IgG2a,k) to Human TLR4
Dog, Guinea pig, Rat, Pig, Human, Monkey
Flo IF IHC IHC-P
Unconjugated
TLR4 Antibody (aa420-435) IHC-plus™ LS-B8183
Anti-TLR4 antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8183 dilution 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
IHC analysis of TLR4 using TLR4 antibody, tested in formalin-fixed paraffin-embedded mouse spleen tissue.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal to Human TLR4
Mouse, Human
ICC IHC IHC-P WB
Unconjugated
TLR4 Antibody (clone HTA125, RPE) LS-C210261

Mouse Monoclonal [clone HTA125] (IgG2a) to Human TLR4
Dog, Human, Monkey
Flo Func IF IP WB
RPE Conjugated
TLR4 Antibody (Low Endotoxin) LS-C44224

Mouse Monoclonal (IgG2a) to Human TLR4
Dog, Guinea pig, Pig, Rhesus monkey, Human
Flo Func IP WB
Unconjugated, Low Endotoxin
TLR4 Antibody LS-C403752
Immunohistochemistry of Human liver cancer using TLR4 Polyclonal Antibody at dilution of 1:25.
Immunohistochemistry of Human gastric cancer using TLR4 Polyclonal Antibody at dilution of 1:25.

Rabbit Polyclonal (IgG) to Human TLR4
Mouse, Rat, Human
ELISA IHC WB
Unconjugated
TLR4 Antibody (N-Terminus) LS-C430
Immunohistochemistry of TLR4 in human spleen tissue with TLR4 antibody at 2.5 µg/ml.
Immunocytochemistry of TLR4 in K562 cells with TLR4 antibody at 2 µg/ml.

Rabbit Polyclonal (IgG) to Human TLR4
Human
ICC WB
Unconjugated

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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