TLR3

toll-like receptor 3

TLR3 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene.

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Products

Proteins (8)

Type

Recombinant (8)

Target

TLR3 (8)

Publications

No (8)

Tag

GST, N-terminus (1)

His (2)

His,C-terminus (1)

His-GST (1)

His-GST, N-terminus (1)

His-S (1)

Species

Human (3)

Mouse (4)

Rat (1)

Source

E. coli (5)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (2)

Biologically Active

Biologically active (1)

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Human TLR3 Protein (Recombinant) - LS-G146

Source:

HEK 293 Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

77.4 kDa

Price:

5 µg/$268; 25 µg/$349

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Mouse TLR3 Protein (Recombinant His-GST) (aa727-905) - LS-G14599

Source:

E. coli

Tag:

His-GST

Molecular Weight:

53.4 kDa

Price:

10 µg/$281; 50 µg/$440; 100 µg/$702; 200 µg/$877; 1 mg/$1,983; 500 µg/$1,523; 5 mg/$3,067; 2 mg/$2,170

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Rat TLR3 Protein (Recombinant His-GST, N-terminus) (Ser381-Asp699) - LS-G133266

Source:

E. coli

Tag:

His-GST, N-terminus

Molecular Weight:

66.2kDa

Price:

10 µg/$260; 50 µg/$335; 200 µg/$622; 100 µg/$497; 1 mg/$1,588; 500 µg/$1,185; 5 mg/$2,522; 2 mg/$1,760

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Mouse TLR3 Protein (Recombinant His,C-terminus) (Met1-Leu705) - LS-G138174

Source:

HEK 293 Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

78.7 kDa

Price:

100 µg/$721

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Human TLR3 Protein (Recombinant GST, N-terminus) (aa601-700) - LS-G60372

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human TLR3 Protein (Recombinant His-S) (aa404-532) - LS-G14595

Source:

E. coli

Tag:

His-S

Molecular Weight:

20.4 kDa

Price:

10 µg/$255; 50 µg/$323; 100 µg/$450; 200 µg/$562; 1 mg/$1,480; 500 µg/$1,096; 5 mg/$2,395; 2 mg/$1,646

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Mouse TLR3 Protein (Recombinant His) (aa574-713) - LS-G14594

Source:

E. coli

Tag:

His

Molecular Weight:

17.6 kDa

Price:

10 µg/$281; 50 µg/$440; 100 µg/$702; 200 µg/$877; 1 mg/$1,983; 500 µg/$1,523; 5 mg/$3,067; 2 mg/$2,170

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Mouse TLR3 Protein (Recombinant His) (aa533-705) - LS-G14596

Source:

E. coli

Tag:

His

Molecular Weight:

21.4 kDa

Price:

10 µg/$281; 50 µg/$440; 100 µg/$702; 200 µg/$877; 1 mg/$1,983; 500 µg/$1,523; 5 mg/$3,067; 2 mg/$2,170

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