Products
Research Areas
COVID-19
Resources
Contact Us
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Cart
How To Buy
Contact Us

Locations

Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464

Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers


Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us


Additional Contact Details

Distributors
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

TLR2

toll-like receptor 2

Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.

Gene Name: toll-like receptor 2
Family/Subfamily: Toll-like Receptor , not assigned-Toll-like Receptor
Synonyms: TLR2, CD282 antigen, CD282, TIL4, Toll-like receptor 2
Target Sequences: NM_003264 NP_003255.2 O60603

Publications (12)

1
High-mobility group box 1 activates integrin-dependent homing of endothelial progenitor cells. Chavakis E, Hain A, Vinci M, Carmona G, Bianchi ME, Vajkoczy P, Zeiher AM, Chavakis T, Dimmeler S. Circulation research. 2007 100:204-12. [PubMed:17218606] Related Antibodies: LS-C40823.
2
Bacterial peptidoglycan breaks down intestinal tolerance via mast cell activation: the role of TLR2 and NOD2. Wu L, Feng BS, He SH, Zheng PY, Croitoru K, Yang PC. Immunology and cell biology. 2007 85:538-45. [PubMed:17563761] Related Antibodies: LS-C98266.
3
Vibrio vulnificus IlpA-induced cytokine production is mediated by Toll-like receptor 2. Goo SY, Han YS, Kim WH, Lee KH, Park SJ. The Journal of biological chemistry. 2007 282:27647-58. [PubMed:17640874] Related Antibodies: LS-C40823.
4
Bovine monocyte TLR2 receptors differentially regulate the intracellular fate of Mycobacterium avium subsp. paratuberculosis and Mycobacterium avium subsp. avium. Weiss DJ, Souza CD, Evanson OA, Sanders M, Rutherford M. Journal of leukocyte biology. 2008 83:48-55. [PubMed:17913973] Related Antibodies: LS-C40823.
5
Monocytes differentiated with GM-CSF and IL-15 initiate Th17 and Th1 responses that are contact-dependent and mediated by IL-15. Harris KM. Journal of leukocyte biology. 2011 90:727-34. [PubMed:21724805] Related Antibodies: LS-C40823.
6
Structural determination and Toll-like receptor 2-dependent proinflammatory activity of dimycolyl-diarabino-glycerol from Mycobacterium marinum. Elass-Rochard E, Rombouts Y, Coddeville B, Maes E, Blervaque R, Hot D, Kremer L, Gurardel Y. The Journal of biological chemistry. 2012 287:34432-44. [PubMed:22798072] [PMC:PMC3464548] Related Antibodies: LS-C40823.
7
Activation of MyD88-dependent TLR1/2 signaling by misfolded a-synuclein, a protein linked to neurodegenerative disorders. Daniele SG, Béraud D, Davenport C, Cheng K, Yin H, Maguire-Zeiss KA. Science signaling. 2015 8:ra45. (WB; Mouse) [Full Text Article] [PubMed:25969543] [PMC:PMC4601639] Related Antibodies: LS-C98268.
8
A comparison of the impact of Shimen and C strains of classical swine fever virus on Toll-like receptor expression. Cao Z, Guo K, Zheng M, Ning P, Li H, Kang K, Lin Z, Zhang C, Liang W, Zhang Y. The Journal of general virology. 2015 96:1732-45. (WB; Human) [Full Text Article] [PubMed:25805409] Related Antibodies: LS-C116906.
9
Tissue expression of Toll-like receptors 2, 3, 4 and 7 in swine in response to the Shimen strain of classical swine fever virus. Cao Z, Zheng M, Lv H, Guo K, Zhang Y. Molecular medicine reports. 2018 May;17:7122-7130. (Rabbit, Mouse) [Full Text Article] [PubMed:29568891] [PMC:PMC5928672] Related Antibodies: LS-C116906.
10
VB-201, an oxidized phospholipid small molecule, inhibits CD14- and Toll-like receptor-2-dependent innate cell activation and constrains atherosclerosis. Mendel I, Feige E, Yacov N, Salem Y, Levi I, Propheta-Meiran O, Shoham A, Ishai E, George J, Harats D, Breitbart E. Clinical and experimental immunology. 2014 January;175:126-37. [Full Text Article] [PubMed:24116867] [PMC:PMC3898561] Related Antibodies: LS-C10673.
11
Correlation between innate and adaptive immunity response in TB children post BCG vaccination. Is it effective or not?: Cross-sectional study. Rahmini Shabariah, Farsida, Mochammad Hatta, Ilhamjaya Patellongi, Irfan Idris, Arif Santoso, Andi Asadul Islam, Rosdiana Natzir, Bob Wahyudin, Warsinggih, Sanjoyo. Annals of medicine and surgery (2012). 2022 May;77:103586. [Full Text Article] [PubMed:35638072] [PMC:PMC9142374]
12
Comparison TLR2 and TLR4 serum levels in children with pulmonary and extrapulmonary tuberculosis with and without a Bacillus Calmette-Guérin (BCG) scar. Rahmini Shabariah, Mochammad Hatta, Irfan Idris, Arif Santoso, Ilhamjaya Patellongi, Tria Astika Endah Permatasari, Farsida, Andi Asadul Islam, Rosdiana Natzir, Bob Wahyudin, Warsinggih, Emilda. Journal of clinical tuberculosis and other mycobacterial diseases. 2021 December;25:100272. [Full Text Article] [PubMed:34504953] [PMC:PMC8416952]
more

☰ Filters
Products
Proteins (14)
Over-Expression Lysate (2)
Recombinant (12)
TLR2 (14)
No (14)
6His-SUMO, N-terminus (1)
GST, N-terminus (2)
His (6)
His-GST (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (9)
Mouse (2)
Rat (2)
293T Cells (1)
Baculovirus (3)
E. coli (6)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (4)
Low endotoxin level (4)
TLR2 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Human TLR2 Protein (Recombinant 6His-SUMO, N-terminus) (aa19-588) - LS-G56583
E. coli
6His-SUMO, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Select
Mouse TLR2 Protein (Recombinant His) (Met1-Gln587) - LS-G98295
Baculovirus
His
Less than 1.0 EU/µg protein (determined by LAL method).
64.8 kDa
100 µg/$721
Select
Human TLR2 Protein (Recombinant His) (aa644-784) - LS-G12620
E. coli
His
22.7 kDa
10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
TLR2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Human TLR2 Protein (Recombinant GST, N-terminus) (aa121-220) - LS-G60370
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
TLR2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Human TLR2 Protein (Recombinant GST, N-terminus) (aa201-300) - LS-G60371
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
TLR2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
TLR2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117455
HEK 293 Cells
Myc-DDK (Flag)
89.7 kDa
100 µg/$494
TLR2 Protein - Purified recombinant protein TLR2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
Human TLR2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68316
HEK 293 Cells
Myc-DDK (Flag)
89.7 kDa
20 µg/$1,107
TLR2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
Human TLR2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81916
293T Cells
Myc-DDK (Flag)
89.7 kDa
20 µg/$150
Select
Human TLR2 Protein (Recombinant His) (Met1-Arg587) - LS-G98673
Baculovirus
His
Less than 1.0 EU/µg protein (determined by LAL method).
65.8 kDa
100 µg/$721
Select
Rat TLR2 Protein (Recombinant His) (Met1-Gln587) - LS-G98485
Baculovirus
His
Less than 1.0 EU/µg protein (determined by LAL method).
67.5 kDa
100 µg/$721
Select
Human TLR2 Protein (Recombinant His) (aa21-190) - LS-G141056
E. coli
169 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
18.7 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
Select
Human TLR2 Protein (Recombinant His) (aa47-245) - LS-G12616
E. coli
His
23.9 kDa
10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
TLR2 Protein - Recombinant Toll Like Receptor 2 By SDS-PAGE
Select
Rat TLR2 Protein (Recombinant His-GST) (aa595-760) - LS-G12619
E. coli
His-GST
51.8 kDa
10 µg/$277; 50 µg/$417; 100 µg/$667; 200 µg/$832; 1 mg/$1,922; 500 µg/$1,470; 5 mg/$3,329
TLR2 Protein - Recombinant Toll Like Receptor 2 By SDS-PAGE
Select
Mouse TLR2 Protein (Recombinant His-T7) (aa25-250) - LS-G12628
E. coli
His-T7
28.8 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
Viewing 1-14 of 14 product results

(0) Selected Add Selected To Cart Compare Selected Clear Selected Top Of Search
Filtered By:
Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

Family of Companies
Site Links Home All Antibodies How To Buy All Proteins Distributors All ELISA & Assay Kits Reviews PathPlus™ Antibodies
Follow LSBio View Cart Register or Login
Copyright © 2022 LifeSpan BioSciences, Inc - Privacy Policy
Contact Us

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464

Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

To place an order:
Orders@LSBio.com

For questions about orders:
Customer.Support@LSBio.com

For technical assistance:
Technical.Support@LSBio.com