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TLR10

toll-like receptor 10

TLR10 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.

Gene Name: toll-like receptor 10
Family/Subfamily: Toll-like Receptor , not assigned-Toll-like Receptor
Synonyms: TLR10, CD290, CD290 antigen, Toll-like receptor 10
Target Sequences: NM_030956 NP_112218.2 Q9BXR5

Publications (1)

1
Cutting-Edge Report: TLR10 Plays a Role in Mediating Bacterial Peptidoglycan-Induced Trophoblast Apoptosis. Bai JZ, Lipski J. American journal of reproductive immunology (New York, N.Y. : 1989). 2012 (IHC, WB; Human) [PubMed:23279063] [PMC:PMC3620725]

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TLR10 ELISA Kit
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1 Plate/$783
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Colorimetric - 450nm (TMB)
1 Plate/$783
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Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).