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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TJP2 / ZO2 / ZO-2

tight junction protein 2

TJP2 / ZO2 / ZO-2 is a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.

Gene Name: tight junction protein 2
Family/Subfamily: Occludin , not assigned-Occludin
Synonyms: TJP2, C9DUPq21.11, DUP9q21.11, DFNA51, ZO-2, Zona occludens 2, Zonula occludens protein 2, Tight junction protein 2, Tight junction protein ZO-2, ZO2, X104, Zona occludens protein 2
Target Sequences: NM_004817 NP_004808.2 Q9UDY2

Filtered By: None
Target
TJP2 / ZO2 / ZO-2 (76)
Reactivity
Human (75)
Mouse (22)
Rat (17)
Bovine (5)
Chicken (4)
Chimpanzee (6)
Dog (31)
Gibbon (6)
Guinea pig (5)
Horse (1)
Monkey (1)
Pig (5)
Rabbit (4)
Application
IHC (17)
IHC-Fr (3)
IHC-P (4)
WB (66)
DB (8)
ELISA (32)
ICC (2)
IF (25)
IP (9)
Peptide-ELISA (2)
Host
rabbit (67)
mouse (7)
guinea pig (2)
Isotype
IgG (61)
IgG1,k (7)
Clonality
monoclonal mc (7)
polyclonal pc (69)
Format
AP Conjugated (6)
APC (1)
APC Conjugated (7)
Azide-free (2)
Biotin Conjugated (10)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (10)
HRP Conjugated (9)
PE Conjugated (7)
Unconjugated (25)
Epitope
aa307-669 (10)
aa981-1009 (8)
pSer978 (8)
C-Terminus (5)
aa468-517 (4)
Internal (2)
aa411-467 (2)
aa1063-1112 (1)
aa1149-1167 (1)
aa1171-1190 (1)
aa150-200 (1)
aa740-790 (1)
aa900-950 (1)
pTyr1118 (1)
Publications
No (75)
Yes (1)
Showing 1-25 of 76 results

TJP2 / ZO2 / ZO-2 Antibody (C-Terminus) IHC-plus™ LS-B2185
Publications (1)
Publications (1)
Rabbit Polyclonal to Human TJP2 / ZO2 / ZO-2
Mouse, Dog, Rat, Human
IF IHC IHC-P WB
Unconjugated
50µg 0.25mg/ml  $485.00
Anti-TJP2 / ZO-2 antibody IHC of human placenta, intermediate trophoblasts. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Anti-TJP2 / ZO-2 antibody IHC of human placenta, intermediate trophoblasts. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

TJP2 / ZO2 / ZO-2 Antibody (AP) LS-C512161
Rabbit Polyclonal (IgG) to Human TJP2 / ZO2 / ZO-2
Mouse, Dog, Rat, Human
IF WB
AP Conjugated
100µl  $815.00

TJP2 / ZO2 / ZO-2 Antibody (aa1171-1190) LS-C313092
Rabbit Polyclonal to Human TJP2 / ZO2 / ZO-2
Human, Monkey
IHC IHC-Fr IHC-P WB
Unconjugated
100µg 200µl 0.5mg/ml  $305.00
TJP2 / ZO2 / ZO-2 antibody. IHC(P): Human Intestinal Cancer Tissue.
WB of TJP2 / ZO2 / ZO-2 antibody. Lane 1: 293T Cell Lysate. Lane 2: MCF-7 Cell Lysate.
TJP2 / ZO2 / ZO-2 antibody. IHC(P): Human Intestinal Cancer Tissue.
WB of TJP2 / ZO2 / ZO-2 antibody. Lane 1: 293T Cell Lysate. Lane 2: MCF-7 Cell Lysate.

TJP2 / ZO2 / ZO-2 Antibody (Internal) LS-C26437
Mouse Monoclonal (IgG1,k) to Human TJP2 / ZO2 / ZO-2
Dog, Human
ELISA IF IP WB
Unconjugated
100µg 0.5mg/ml  $605.00

TJP2 / ZO2 / ZO-2 Antibody (HRP) LS-C550356
Mouse Monoclonal (IgG1,k) to Human TJP2 / ZO2 / ZO-2
Dog, Human
ELISA IF IP WB
HRP Conjugated
100µl  $755.00

TJP2 / ZO2 / ZO-2 Antibody (Biotin) LS-C530272
Mouse Monoclonal (IgG1,k) to Human TJP2 / ZO2 / ZO-2
Dog, Human
ELISA IF IP WB
Biotin Conjugated
100µl  $755.00

TJP2 / ZO2 / ZO-2 Antibody (FITC) LS-C540182
Mouse Monoclonal (IgG1,k) to Human TJP2 / ZO2 / ZO-2
Dog, Human
ELISA IF IP WB
FITC Conjugated
100µl  $755.00

TJP2 / ZO2 / ZO-2 Antibody (AP) LS-C512157
Mouse Monoclonal (IgG1,k) to Human TJP2 / ZO2 / ZO-2
Dog, Human
ELISA IF IP WB
AP Conjugated
100µl  $755.00

TJP2 / ZO2 / ZO-2 Antibody (APC) LS-C519927
Mouse Monoclonal (IgG1,k) to Human TJP2 / ZO2 / ZO-2
Dog, Human
ELISA IF IP WB
APC Conjugated
100µl  $755.00

TJP2 / ZO2 / ZO-2 Antibody (PE) LS-C658319
Mouse Monoclonal (IgG1,k) to Human TJP2 / ZO2 / ZO-2
Dog, Human
ELISA IF IP WB
PE Conjugated
100µl  $755.00

TJP2 / ZO2 / ZO-2 Antibody LS-C354980
Rabbit Polyclonal (IgG) to Human TJP2 / ZO2 / ZO-2
Mouse, Dog, Human
ELISA IF IHC WB
Unconjugated
100µg  $395.00
Immunofluorescence analysis of ZO2/TJP2 Antibody was done on 90% confluent log phase CaCo2 cells. The cells were fixed with 4% paraformaldehyde for 15 minutes, permeabilized with 0.25% Triton X-100 for 10 minutes, and blocked with 5% BSA for 1 hour at room temperature. The cells were labeled with ZO2/TJP2 Antibody at 1 µg/mL in 1% BSA and incubated for 3 hours at room temperature and then labeled with Alexa Fluor 488 Goat Anti-Rabbit IgG Secondary Antibody at a dilution of 1:400 for 45 minutes at room temperature (Panel a: green). Nuclei (Panel b: blue) were stained with DAPI. F-actin (Panel c: red) was stained with Alexa Fluor 594 Phalloidin. Panel d is a merged image showing membrane localization. Panel e is a no primary antibody control. The images were captured at 40X magnification.
WB using ZO-2 / TJP2 Antibody
Immunofluorescence analysis of ZO2/TJP2 Antibody was done on 90% confluent log phase CaCo2 cells. The cells were fixed with 4% paraformaldehyde for 15 minutes, permeabilized with 0.25% Triton X-100 for 10 minutes, and blocked with 5% BSA for 1 hour at room temperature. The cells were labeled with ZO2/TJP2 Antibody at 1 µg/mL in 1% BSA and incubated for 3 hours at room temperature and then labeled with Alexa Fluor 488 Goat Anti-Rabbit IgG Secondary Antibody at a dilution of 1:400 for 45 minutes at room temperature (Panel a: green). Nuclei (Panel b: blue) were stained with DAPI. F-actin (Panel c: red) was stained with Alexa Fluor 594 Phalloidin. Panel d is a merged image showing membrane localization. Panel e is a no primary antibody control. The images were captured at 40X magnification.
WB using ZO-2 / TJP2 Antibody

TJP2 / ZO2 / ZO-2 Antibody IHC-plus™ LS-B14372
Rabbit Polyclonal (IgG) to Human TJP2 / ZO2 / ZO-2
Mouse, Rat, Human
IHC IHC-P WB
Unconjugated
50µl  $425.00
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

TJP2 / ZO2 / ZO-2 Antibody (aa411-467) LS-C124821
Guinea pig Polyclonal to Human TJP2 / ZO2 / ZO-2
Mouse, Human
IF IHC IHC-Fr WB
Unconjugated
100µg  $800.00

TJP2 / ZO2 / ZO-2 Antibody (aa411-467) LS-C140252
Guinea pig Polyclonal (IgG) to Human TJP2 / ZO2 / ZO-2
Mouse, Human
IF IHC IHC-Fr WB
Unconjugated
100µg  $495.00

TJP2 / ZO2 / ZO-2 Antibody LS-C660824
Rabbit Polyclonal (IgG) to Human TJP2 / ZO2 / ZO-2
Human
ELISA IF WB
Unconjugated
100µg  $435.00

TJP2 / ZO2 / ZO-2 Antibody (aa1149-1167) LS-C313100
Rabbit Polyclonal to Mouse TJP2 / ZO2 / ZO-2
Mouse, Rat
IHC IHC-P WB
Unconjugated
100µg 200µl 0.5mg/ml  $305.00
TJP2 / ZO2 / ZO-2 antibody. IHC(P): Mouse Liver Tissue.
WB of TJP2 / ZO2 / ZO-2 antibody. Lane 1: Rat Brain Tissue Lysate. Lane 2: PC-12 Cell Lysate. Lane 3: Mouse Brain Tissue Lysate. Lane 4: HEPA Cell Lysate.
TJP2 / ZO2 / ZO-2 antibody. IHC(P): Mouse Liver Tissue.
WB of TJP2 / ZO2 / ZO-2 antibody. Lane 1: Rat Brain Tissue Lysate. Lane 2: PC-12 Cell Lysate. Lane 3: Mouse Brain Tissue Lysate. Lane 4: HEPA Cell Lysate.

TJP2 / ZO2 / ZO-2 Antibody LS-C26436
Rabbit Polyclonal (IgG) to Dog TJP2 / ZO2 / ZO-2
Mouse, Dog, Human
ELISA IHC WB
Unconjugated
100µg  $605.00

TJP2 / ZO2 / ZO-2 Antibody (aa740-790) LS-C483078
Rabbit Polyclonal to Human TJP2 / ZO2 / ZO-2
Human
IHC
Unconjugated
100µl  $325.00
Rabbit antibody to ZO2 (740-790). IHC on paraffin sections of human large intestine tissue using Rabbit antibody to ZO2 (740-790). HIER: 1 mM EDTA, pH 8 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered through a 0.2 micron filter. Detection was done using Novolink HRP polymer from Leica following manufacturer's instructions. Primary antibody: dilution 1:1000, incubated 30 min at RT (using Autostainer). Sections were counterstained with Harris Hematoxylin.
Rabbit antibody to ZO2 (740-790). IHC on paraffin sections of human skin tissue using Rabbit antibody to ZO2 (740-790). HIER: 1 mM EDTA, pH 8 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered through a 0.2 micron filter. Detection was done using Novolink HRP polymer from Leica following manufacturer's instructions. Primary antibody: dilution 1:1000, incubated 30 min at RT (using Autostainer). Sections were counterstained with Harris Hematoxylin.
Rabbit antibody to ZO2 (740-790). IHC on paraffin sections of human large intestine tissue using Rabbit antibody to ZO2 (740-790). HIER: 1 mM EDTA, pH 8 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered through a 0.2 micron filter. Detection was done using Novolink HRP polymer from Leica following manufacturer's instructions. Primary antibody: dilution 1:1000, incubated 30 min at RT (using Autostainer). Sections were counterstained with Harris Hematoxylin.
Rabbit antibody to ZO2 (740-790). IHC on paraffin sections of human skin tissue using Rabbit antibody to ZO2 (740-790). HIER: 1 mM EDTA, pH 8 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered through a 0.2 micron filter. Detection was done using Novolink HRP polymer from Leica following manufacturer's instructions. Primary antibody: dilution 1:1000, incubated 30 min at RT (using Autostainer). Sections were counterstained with Harris Hematoxylin.

TJP2 / ZO2 / ZO-2 Antibody (Internal) LS-C26438
Rabbit Polyclonal (IgG) to Human TJP2 / ZO2 / ZO-2
Human
IF WB
Unconjugated
100µg  $605.00

TJP2 / ZO2 / ZO-2 Antibody (AP) LS-C512160
Rabbit Polyclonal (IgG) to Human TJP2 / ZO2 / ZO-2
Human
IF WB
AP Conjugated
100µl  $755.00

TJP2 / ZO2 / ZO-2 Antibody (APC) LS-C519928
Rabbit Polyclonal (IgG) to Human TJP2 / ZO2 / ZO-2
Human
IF WB
APC Conjugated
100µl  $755.00

TJP2 / ZO2 / ZO-2 Antibody (aa307-669) LS-C373327
Rabbit Polyclonal (IgG) to Human TJP2 / ZO2 / ZO-2
Human
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $530.00; 10ml 0.5mg/ml  $2,100.00
Western blot of TJP2 / ZO2 / ZO-2 antibody.
Western blot of TJP2 / ZO2 / ZO-2 antibody.

TJP2 / ZO2 / ZO-2 Antibody (phospho-Tyr1118) LS-C291537
Rabbit Polyclonal (IgG) to Human TJP2 / ZO2 / ZO-2
Mouse, Rat, Human
ELISA Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Western blot analysis of lysates from brain tissue, using phospho-ZO-2 (Phospho-Y1118) antibody.
Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using ZO-2 (Phospho-Y1118) Antibody
Western blot analysis of lysates from brain tissue, using phospho-ZO-2 (Phospho-Y1118) antibody.
Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using ZO-2 (Phospho-Y1118) Antibody

TJP2 / ZO2 / ZO-2 Antibody (aa981-1009) LS-C330224
Rabbit Polyclonal (IgG) to Human TJP2 / ZO2 / ZO-2
Human
ELISA WB
Unconjugated
200µl  $530.00

TJP2 / ZO2 / ZO-2 Antibody LS-C386772
Rabbit Polyclonal (IgG) to Human TJP2 / ZO2 / ZO-2
Mouse, Rat, Human
ELISA WB
Unconjugated
100µl 1mg/ml  $265.00
Showing 1-25 of 76 results

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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