TIRAP

toll-interleukin 1 receptor (TIR) domain containing adaptor protein

The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described.

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Products

Proteins (7)

Type

Over-Expression Lysate (2)

Recombinant (5)

Target

TIRAP (7)

Publications

No (7)

Tag

GST (1)

GST, N-terminus (1)

His (1)

His-GST (1)

Myc-DDK (Flag) (3)

Species

Human (6)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (3)

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Human TIRAP Protein (Recombinant His) - LS-G1894

Source:

E. coli

Tag:

His

Price:

50 µg/$411; 250 µg/$985; 10 µg/$276

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Human TIRAP Protein (Recombinant GST, N-terminus) (aa1-221) - LS-G56582

Source:

E. coli

Tag:

GST, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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TIRAP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G120652

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28.03 kDa

Price:

100 µg/$494

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Human TIRAP Protein (Recombinant His-GST) (aa1-221) - LS-G26211

Source:

E. coli

Tag:

His-GST

Molecular Weight:

31.3 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Human TIRAP Protein (Recombinant GST) (Full Length) - LS-G36172

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

53.9 kDa

Price:

10 µg/$479; 25 µg/$670

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Human TIRAP Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68651

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

23.7 kDa

Price:

20 µg/$1,107

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Human TIRAP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82705

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28.03 kDa

Price:

20 µg/$150

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