TIPIN

TIMELESS interacting protein

Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Important for cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHEK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. Forms a complex with TIMELESS and this complex regulates DNA replication processes under both normal and stress conditions, stabilizes replication forks and influences both CHEK1 phosphorylation and the intra-S phase checkpoint in response to genotoxic stress.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

TIPIN (5)

Publications

No (5)

Tag

GST (1)

His (1)

His, N-Terminal (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (2)

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Human TIPIN Protein (Recombinant His, N-Terminal) - LS-G143865

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

33.1 kDa

Price:

50 µg/$419

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Human TIPIN Protein (Recombinant His) - LS-G2559

Source:

E. coli

Tag:

His

Price:

50 µg/$361; 250 µg/$739; 10 µg/$261

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Human TIPIN Protein (Recombinant GST) (Full Length) - LS-G34131

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

58.85 kDa

Price:

10 µg/$479; 25 µg/$670

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Human TIPIN Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83894

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.3 kDa

Price:

20 µg/$150

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TIPIN Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101531

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.3 kDa

Price:

100 µg/$494

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