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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TIMP2

TIMP metallopeptidase inhibitor 2

TIMP2 is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.

Gene Name: TIMP metallopeptidase inhibitor 2
Synonyms: TIMP2, Metalloproteinase inhibitor 2, TIMP-2, CSC-21K
Target Sequences: NM_003255 NP_003246.1 P16035

Filtered by: None
Type
Native (1)
Over-Expression Lysate (2)
Recombinant (22)
Target
TIMP2 (25)
Tag
6His,C-terminus (3)
6His,N-terminus (1)
Fc (1)
GST (2)
His (8)
His + T7 (1)
Myc + DDK (3)
Species
Bovine (1)
Dog (1)
Horse (1)
Human (18)
Mouse (2)
Rat (1)
Source
293T Cells (1)
CHO Cells (1)
E. coli (11)
HEK 293 Cells (5)
Human (2)
Human Cells (3)
Sf9 Cells (1)
Wheat Germ Extract (1)
Purification
Purified (19)
Low Endotoxin Level
Low endotoxin level (7)
Biologically Active
Biologically active (4)
Publications
No (25)
Showing 1-25 of 25 results

Rat TIMP2 Protein (Recombinant 6His,N-terminus) (aa27-220) - LS-G11640
E. coli
6His,N-terminus
23.2 kDa
10µg  $295.00; 50µg  $495.00; 100µg  $695.00; 200µg  $1,005.00; 1mg  $2,580.00; 500µg  $1,140.00
Recombinant Tissue Inhibitors Of Metalloproteinase 2 By SDS-PAGE

Mouse TIMP2 Protein (Recombinant His) (aa27-220) - LS-G11638
E. coli
His
23.2 kDa
10µg  $295.00; 50µg  $495.00; 100µg  $695.00; 200µg  $1,005.00; 1mg  $2,580.00; 500µg  $1,140.00
Recombinant Tissue Inhibitors Of Metalloproteinase 2 By SDS-PAGE

Human TIMP2 Protein (Recombinant His) - LS-G23924
HEK 293 Cells
His
23.4 kDa
10µg  $335.00; 50µg  $530.00; 100µg  $800.00

Human TIMP2 Protein (Recombinant GST) (aa30-220) - LS-G22362
E. coli
GST
48.8 kD
1mg  $1,290.00; 500µg  $830.00; 200µg  $485.00; 50µg  $275.00; 10µg  $245.00; 100µg  $355.00

Human TIMP2 Protein (Recombinant) (aa27-220) - LS-G55937
Human
None
Less than 1.0 EU/µg protein (determined by LAL method).
23.4kDa
50µg  $590.00; 10µg  $315.00; 200µg  $1,170.00; 100µg  $935.00; 1mg  $3,510.00; 500µg  $1,560.00
Eukaryotic Tissue Inhibitors Of Metalloproteinase 2 By SDS-PAGE

Human TIMP2 Protein (Recombinant Myc + DDK) (Full Length) - LS-G66272
HEK 293 Cells
Myc + DDK
21.7 kDa
20µg  $890.00
Purified recombinant protein TIMP2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining

Human TIMP2 Protein (Recombinant GST) (Full Length) - LS-G30708
Wheat Germ Extract
GST
47.08 kDa
10µg  $425.00; 25µg  $590.00
12.5% SDS-PAGE of human TIMP2 stained with Coomassie Blue

Human TIMP2 Protein (Recombinant) - LS-G17989
E. coli
None
Biologically active
5µg  $195.00; 20µg  $255.00; 1mg  $3,780.00

Human TIMP2 Protein (Recombinant His) - LS-G17865
E. coli
His
5µg  $195.00; 20µg  $255.00; 1mg  $2,850.00

Human TIMP2 Protein (Recombinant His) - LS-G1914
E. coli
His
100µg 0.5mg/ml  $315.00; 0.5mg 0.5mg/ml  $695.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

Human TIMP2 Protein (Recombinant) - LS-G432
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
21.8 kDa
2µg  $215.00; 10µg  $285.00

Human TIMP2 Protein (Native) - LS-G5513
Human
None
21.0 kDa
5µg  $425.00

Human TIMP2 Protein (Recombinant) - LS-G137628
CHO Cells
None
Biologically active
Less than 1 EU/µg (determined by LAL method).
Predicted molecular mass of approximately 22 kD. The protein migrates at about 25 kD in DTT-reducing conditions and about 22 kD in non-reducing condition by SDS-PAGE. The N-terminal amino acid is Cys.
10µg 0.2mg/ml  $285.00; 25µg 0.2mg/ml  $405.00; 100µg  $965.00; 500µg  $2,910.00
Activated mouse MMP-9 (100 ng/mL) is inhibited by different concentrations of human TIMP-2.

Human TIMP2 Protein (Recombinant His) - LS-G17340
HEK 293 Cells
His
Biologically active
2µg  $195.00; 10µg  $255.00; 1mg  $4,950.00

Mouse TIMP2 Protein (Recombinant 6His,C-terminus) (Cys27-Pro220) - LS-G51854
Human Cells
6His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
22.5kD
10µg  $265.00; 50µg  $465.00; 500µg  $1,605.00; 1mg  $2,520.00

Human TIMP2 Protein (Recombinant 6His,C-terminus) (aa27-220) - LS-G134663
Sf9 Cells
6His,C-terminus
22.5kDa
1µg  $195.00; 5µg  $255.00; 50µg  $1,260.00

Human TIMP2 Protein (Recombinant Fc) (Cys27-Pro220) - LS-G97463
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
48 kDa
10µg  $415.00; 20µg  $545.00

Human TIMP2 Protein (Recombinant 6His,C-terminus) (Cys27-Pro220) - LS-G38968
Human Cells
6His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
22.79kD
10µg  $265.00; 50µg  $465.00; 500µg  $1,605.00; 1mg  $2,310.00

Human TIMP2 Protein (Recombinant) - LS-G132464
HEK 293 Cells
None
Less than 1.0 EU/µg protein.
22.6 kDa
10µg  $305.00
Human TIMP-2, human recombinant

TIMP2 Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G117464
HEK 293 Cells
Myc + DDK
24.4 kDa
100µg  $365.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

Human TIMP2 Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G77339
293T Cells
Myc + DDK
24.4 kDa
20µg  $195.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

Bovine TIMP2 Protein (Recombinant His + T7) (aa27-220) - LS-G11630
E. coli
His + T7
25.5 kDa
50µg  $530.00; 10µg  $305.00; 200µg  $1,050.00; 100µg  $725.00; 1mg  $2,700.00; 500µg  $1,200.00
Recombinant Tissue Inhibitors Of Metalloproteinase 2 By SDS-PAGE

Horse TIMP2 Protein (Recombinant His) (aa2-88) - LS-G11634
E. coli
His
11.1 kDa
10µg  $295.00; 50µg  $495.00; 100µg  $695.00; 200µg  $1,005.00; 1mg  $2,580.00; 500µg  $1,140.00
Recombinant Tissue Inhibitors Of Metalloproteinase 2 By SDS-PAGE

Dog TIMP2 Protein (Recombinant His) (aa33-153) - LS-G11635
E. coli
His
15.0 kDa
10µg  $295.00; 50µg  $485.00; 100µg  $680.00; 200µg  $980.00; 1mg  $2,535.00; 500µg  $1,125.00
Recombinant Tissue Inhibitors Of Metalloproteinase 2 By SDS-PAGE

Human TIMP2 Protein (Recombinant His) (aa27-220) - LS-G11636
E. coli
His
23.3 kDa
10µg  $255.00; 50µg  $405.00; 100µg  $495.00; 200µg  $740.00; 1mg  $1,890.00; 500µg  $845.00
Recombinant Tissue Inhibitors Of Metalloproteinase 2 By SDS-PAGE
Showing 1-25 of 25 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).