TIMP2

TIMP metallopeptidase inhibitor 2

TIMP2 is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.

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Products

Proteins (22)

Type

Over-Expression Lysate (2)

Recombinant (20)

Target

TIMP2 (22)

Publications

No (22)

Tag

6His, C-terminus (4)

6His, N-terminus (1)

Fc (1)

GST (2)

His (6)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Bovine (1)

Dog (1)

Horse (1)

Human (14)

Mouse (3)

Rat (1)

Source

293T Cells (1)

CHO Cells (1)

E. coli (9)

HEK 293 Cells (4)

Human (1)

Human Cells (3)

Mammalian Cells (2)

Wheat Germ Extract (1)

Purification

Purified (6)

Low Endotoxin Level

Low endotoxin level (8)

Biologically Active

Biologically active (1)

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Rat TIMP2 Protein (Recombinant 6His, N-terminus) (aa27-220) - LS-G11640

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

23.2 kDa

Price:

10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284

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Human TIMP2 Protein (Recombinant His) (aa27-220) - LS-G11636

Source:

E. coli

Tag:

His

Molecular Weight:

23.3 kDa

Price:

10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,838

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Mouse TIMP2 Protein (Recombinant His) (aa27-220) - LS-G11638

Source:

E. coli

Tag:

His

Molecular Weight:

23.2 kDa

Price:

10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284

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Human TIMP2 Protein (Recombinant) - LS-G137628

Source:

CHO Cells

Tag:

None

Endotoxin Level:

Less than 1 EU/µg (determined by LAL method).

Molecular Weight:

Predicted molecular mass of approximately 22 kD. The protein migrates at about 25 kD in DTT-reducing conditions and about 22 kD in non-reducing condition by SDS-PAGE. The N-terminal amino acid is Cys.

Price:

25 µg/$497

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Human TIMP2 Protein (Recombinant) (Cys27-Pro220) - LS-G138398

Source:

HEK 293 Cells

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

22 kDa

Price:

20 µg/$502

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TIMP2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117464

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

24.4 kDa

Price:

100 µg/$494

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Human TIMP2 Protein (Recombinant GST) (Full Length) - LS-G30708

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

47.08 kDa

Price:

10 µg/$479; 25 µg/$670

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Human TIMP2 Protein (Recombinant His) - LS-G23924

Source:

HEK 293 Cells

Tag:

His

Molecular Weight:

23.4 kDa

Price:

10 µg/$341; 50 µg/$652; 100 µg/$977

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Human TIMP2 Protein (Recombinant GST) (aa30-220) - LS-G22362

Source:

E. coli

Tag:

GST

Molecular Weight:

48.8 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human TIMP2 Protein (Recombinant) (aa27-220) - LS-G55937

Source:

Human

Tag:

None

Molecular Weight:

23.4kDa

Price:

50 µg/$652; 10 µg/$315; 200 µg/$1,228; 100 µg/$1,034; 1 mg/$2,469; 500 µg/$1,971; 5 mg/$4,551; 2 mg/$2,661

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Human TIMP2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66272

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

21.7 kDa

Price:

20 µg/$1,107

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Human TIMP2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77339

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

24.4 kDa

Price:

20 µg/$150

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Human TIMP2 Protein (Recombinant) - LS-G432

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

21.8 kDa

Price:

2 µg/$268; 10 µg/$349

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Human TIMP2 Protein (Recombinant His) - LS-G1914

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human TIMP2 Protein (Recombinant 6His, C-terminus) (Cys27-Pro220) - LS-G140419

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

22.8 kDa

Price:

10 µg/$317; 50 µg/$524

Select

Mouse TIMP2 Protein (Recombinant 6His, C-terminus) (Cys27-Pro220) - LS-G140663

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

22.5 kDa

Price:

10 µg/$344; 50 µg/$584

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Mouse TIMP2 Protein (Recombinant 6His, C-terminus) (Cys27-Pro220) - LS-G51854

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

22.5kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353

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Human TIMP2 Protein (Recombinant 6His, C-terminus) (Cys27-Pro220) - LS-G38968

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

22.79kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157

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Human TIMP2 Protein (Recombinant Fc) (Cys27-Pro220) - LS-G97463

Source:

Human Cells

Tag:

Fc

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

48 kDa

Price:

20 µg/$502

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Bovine TIMP2 Protein (Recombinant His-T7) (aa27-220) - LS-G11630

Source:

E. coli

Tag:

His-T7

Molecular Weight:

25.5 kDa

Price:

50 µg/$502; 10 µg/$291; 200 µg/$1,002; 100 µg/$802; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334

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Dog TIMP2 Protein (Recombinant His) (aa33-153) - LS-G11635

Source:

E. coli

Tag:

His

Molecular Weight:

15.0 kDa

Price:

10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257

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Horse TIMP2 Protein (Recombinant His) (aa2-88) - LS-G11634

Source:

E. coli

Tag:

His

Molecular Weight:

11.1 kDa

Price:

10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284

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