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Probable mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
Gene Name: | translocase of inner mitochondrial membrane 8 homolog B (yeast) |
Synonyms: | TIMM8B, DDP2, Deafness dystonia protein 2, DDPL, TIM8B, DDP-like protein |
Target Sequences: | NM_012459 |
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