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TIMM22

translocase of inner mitochondrial membrane 22 homolog (yeast)

Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.

Gene Name:	translocase of inner mitochondrial membrane 22 homolog (yeast)
Synonyms:	TIMM22, TEX4, Putative membrane protein, Testis-expressed sequence 4, TIM22
Target Sequences:	NM_013337 NP_037469.2 Q9Y584

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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