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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TIGAR

chromosome 12 open reading frame 5

TIGAR is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region.

Gene Name: chromosome 12 open reading frame 5
Synonyms: TIGAR, C12orf5, FR2BP
Target Sequences: NM_020375 NP_065108.1 Q9NQ88

Filtered by: None
Target
TIGAR (33)
Reactivity
Human (31)
Mouse (17)
Rat (2)
Dog (1)
Monkey (1)
Application
IHC (16)
IHC-P (6)
WB (24)
ELISA (18)
IF (2)
IP (3)
Host
rabbit (31)
mouse (2)
Isotype
IgG (21)
IgG2b (2)
Clonality
monoclonal mc (2)
polyclonal pc (31)
Clone
Woody-1 (2)
Format
AP Conjugated (1)
APC Conjugated (1)
Biotin Conjugated (3)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (20)
Epitope
aa1-30 (8)
aa50-200 (4)
aa220-270 (3)
aa1-270 (1)
aa140-190 (1)
aa2-203 (1)
aa25-75 (1)
Publications
No (33)
Showing 1-25 of 33 results

IHC-plus™ TIGAR Antibody LS-B1341
Rabbit Polyclonal (IgG) to Human TIGAR
Mouse, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05mg 1mg/ml  $425.00
Anti-C12orf5 / TIGAR antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Immunofluorescence of TIGAR in Human Brain cells with TIGAR antibody at 20 ug/ml.

IHC-plus™ TIGAR Antibody (aa140-190) LS-B6521
Rabbit Polyclonal (IgG) to Human TIGAR
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50µg 0.5mg/ml  $425.00
Anti-C12orf5 / TIGAR antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Western blot of human TIGAR in human liver in the 1) absence and 2) presence of immunizing peptide, 3) mouse liver and 4) rat liver lysate using antibody at 1, 4 and 2 ug/ml, respectively.

IHC-plus™ TIGAR Antibody LS-B462
Rabbit Polyclonal (IgG) to Human TIGAR
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µg 1mg/ml  $545.00
Anti-C12orf5 / TIGAR antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Western blot of TIGAR in EL4 cell lysate with TIGAR antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.

IHC-plus™ TIGAR Antibody (aa220-270) LS-B6520
Rabbit Polyclonal to Human TIGAR
Dog, Human, Monkey
IHC, IHC-P, WB
Unconjugated
50µg 0.5mg/ml  $425.00
Anti-C12orf5 / TIGAR antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Western blot of human TIGAR in MCF7 cell lysate in the 1) absence and 2) presence of immunizing peptide using antibody at 2 ug/ml.

IHC-plus™ TIGAR Antibody (aa25-75) LS-B14303
Rabbit Polyclonal (IgG) to Human TIGAR
Human
IHC, IHC-P, WB
Unconjugated
50µl 1mg/ml  $425.00
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

TIGAR Antibody LS-C502069
Rabbit Polyclonal (IgG) to Human TIGAR
Human
ELISA, IF, IHC
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry of paraffin-embedded human pancreatic cancer using TIGAR Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lung cancer using TIGAR Antibody at dilution of 1:100

IHC-plus™ TIGAR Antibody (aa220-270) LS-B12801
Rabbit Polyclonal (IgG) to Human TIGAR
Human
IHC, IHC-P
Unconjugated
50µl  $425.00
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)

TIGAR Antibody LS-C772124
Rabbit Polyclonal (IgG) to Human TIGAR
Human
ELISA, IHC
Unconjugated
20µl 0.3mg/ml  $205.00; 60µl 0.3mg/ml  $235.00; 120µl 0.3mg/ml  $295.00; 200µl 0.3mg/ml  $395.00

TIGAR Antibody (aa2-203) LS-C348827
Rabbit Polyclonal to Human TIGAR
Human
ELISA, IHC
Unconjugated
100µl 1mg/ml  $255.00
Immunohistochemistry of TIGAR antibody

TIGAR Antibody LS-C406067
Rabbit Polyclonal (IgG) to Human TIGAR
Human
ELISA, IHC
Unconjugated
20µl 0.3mg/ml  $205.00; 60µl 0.3mg/ml  $235.00; 120µl 0.3mg/ml  $295.00; 200µl 0.3mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human breast cancer using C12orf5 Polyclonal Antibody at dilution of 1:80.
Immunohistochemistry of paraffin-embedded Human breast cancer using C12orf5 Polyclonal Antibody at dilution of 1:80.

TIGAR Antibody LS-C180087
Rabbit Polyclonal to Human TIGAR
Mouse, Human
IHC, WB
Unconjugated
100µl 0.5mg/ml  $335.00
Immunohistochemistry: TIGAR Antibody - Analysis of TIGAR in mouse muscle.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot: TIGAR Antibody - Analysis of TIGAR in HeLa whole cell extracts.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TIGAR Antibody (aa50-200, Biotin) LS-C143216
Rabbit Polyclonal to Human TIGAR
Mouse, Human
IHC, WB
Biotin Conjugated
100µl  $365.00
Immunohistochemistry: TIGAR Antibody - Analysis of TIGAR in mouse muscle.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot: TIGAR Antibody - Analysis of TIGAR in HeLa whole cell extracts.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TIGAR Antibody (aa50-200, DY488) LS-C143218
Rabbit Polyclonal to Human TIGAR
Mouse, Human
IHC, WB
DY488 Conjugated
100µl  $365.00
Immunohistochemistry: TIGAR Antibody - Analysis of TIGAR in mouse muscle.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot: TIGAR Antibody - Analysis of TIGAR in HeLa whole cell extracts.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TIGAR Antibody (aa50-200, DY650) LS-C143217
Rabbit Polyclonal to Human TIGAR
Mouse, Human
IHC, WB
DY650 Conjugated
100µl  $365.00
Immunohistochemistry: TIGAR Antibody - Analysis of TIGAR in mouse muscle.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot: TIGAR Antibody - Analysis of TIGAR in HeLa whole cell extracts.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TIGAR Antibody (aa50-200, DY550) LS-C143220
Rabbit Polyclonal to Human TIGAR
Mouse, Human
IHC, WB
DY550 Conjugated
100µl  $365.00
Immunohistochemistry: TIGAR Antibody - Analysis of TIGAR in mouse muscle.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western Blot: TIGAR Antibody - Analysis of TIGAR in HeLa whole cell extracts.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TIGAR Antibody LS-C803595
Rabbit Polyclonal (IgG) to Human TIGAR
Human
ELISA, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00

TIGAR Antibody (aa1-30) LS-C325730
Rabbit Polyclonal (IgG) to Human TIGAR
Mouse, Human
ELISA, WB
Unconjugated
200µl  $590.00

TIGAR Antibody (aa1-30, HRP) LS-C540630
Rabbit Polyclonal (IgG) to Mouse TIGAR
Mouse
ELISA, WB
HRP Conjugated
200µl  $740.00

TIGAR Antibody (aa1-30, Biotin) LS-C520489
Rabbit Polyclonal (IgG) to Mouse TIGAR
Mouse
ELISA, WB
Biotin Conjugated
200µl  $740.00

TIGAR Antibody (aa1-30, FITC) LS-C241800
Rabbit Polyclonal (IgG) to Human TIGAR
Mouse, Human
ELISA, WB
FITC Conjugated
200µl  $740.00

TIGAR Antibody (aa1-30, APC) LS-C241799
Rabbit Polyclonal (IgG) to Human TIGAR
Mouse, Human
ELISA, WB
APC Conjugated
200µl  $740.00

TIGAR Antibody LS-C778668
Rabbit Polyclonal to Human TIGAR
Human
ELISA, WB
Unconjugated
100µg 100µl 1mg/ml  $305.00

TIGAR Antibody (aa220-270) LS-C289040
Rabbit Polyclonal (IgG) to Human TIGAR
Human
IHC, IP
Unconjugated
100µl 1mg/ml  $395.00
Detection of Human TIGAR by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-TIGAR used at a dilution of 1:1000 (1 ug/ml). Detection: DAB.

TIGAR Antibody (aa1-270, clone Woody-1) LS-C746190
Mouse Monoclonal [clone Woody-1] (IgG2b) to Human TIGAR
Human
IP, WB
Unconjugated
50µg  $365.00

TIGAR Antibody (clone Woody-1) LS-C343747
Mouse Monoclonal [clone Woody-1] (IgG2b) to Human TIGAR
Human
IP, WB
Unconjugated
100µg  $415.00
Western blot of human cell lines using monoclonal antibody to TIGAR (human) (Woody-1). Total protein extracts from various human cell lines (293T,THP-1, U937, and HeLa) were run on SDS-PAGE and TIGAR was detected by MAb to TIGAR (human) (Woody-1) at 1:1000 dilution. Anti-mouse IgG coupled horse radish peroxidase was used at 1:5000 dilution for ECL detection.
Showing 1-25 of 33 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).