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TIFA

TRAF-interacting protein with forkhead-associated domain

Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism.

Gene Name: TRAF-interacting protein with forkhead-associated domain
Synonyms: TIFA, TIFAA, T2BP, T6BP, TRAF2 binding protein, TRAF2-binding protein, TRAF6 binding protein
Target Sequences: NP_443096.1 Q96CG3

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Products
Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
TIFA (4)
No (4)
GST (1)
His (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (2)
TIFA Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
21.3 kDa
20 µg/$150
TIFA Protein - 12.5% SDS-PAGE of human TIFA stained with Coomassie Blue
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Wheat Germ Extract
GST
47.8 kDa
10 µg/$479; 25 µg/$670
TIFA Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
21.3 kDa
100 µg/$494
TIFA Protein
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E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
Viewing 1-4 of 4 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).