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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TIE1 / TIE

tyrosine kinase with immunoglobulin-like and EGF-like domains 1

TIE1 / TIE is a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Name: tyrosine kinase with immunoglobulin-like and EGF-like domains 1
Family/Subfamily: Protein Kinase , Tie/Tek
Synonyms: TIE1, JTK14, TIE, Tie-1
Target Sequences: NM_005424 NP_005415.1 P35590

Filtered By: None
Target
TIE1 / TIE (66)
Reactivity
Human (56)
Mouse (29)
Rat (4)
Bovine (1)
Application
IHC (40)
IHC-P (4)
WB (59)
Flo (2)
ELISA (27)
ICC (4)
IF (3)
IP (2)
Host
rabbit (59)
mouse (7)
Isotype
IgG (54)
IgG1 (4)
IgG2a (1)
IgG2a,k (1)
Clonality
monoclonal mc (7)
polyclonal pc (59)
Clone
1G10 (1)
6F12 (1)
8C9 (1)
8D12B10 (1)
8D12D2 (1)
9C1 (1)
Format
AP Conjugated (4)
APC (3)
APC Conjugated (5)
Azide-free (2)
Biotin Conjugated (8)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (8)
HRP Conjugated (6)
PE Conjugated (6)
Unconjugated (23)
Epitope
aa701-898 (10)
aa835-1134 (10)
aa361-389 (8)
aa12-42 (7)
Internal (2)
820-900 aa, Internal (1)
C-Terminus (1)
Extracellular Domain (1)
N-Terminus (1)
Publications
No (66)
Showing 1-25 of 66 results

TIE1 / TIE Antibody (clone 1G10) IHC-plus™ LS-B6397
Mouse Monoclonal [clone 1G10] (IgG2a,k) to Human TIE1 / TIE
Human
ELISA IHC IHC-P WB
Unconjugated
50µg 0.5mg/ml  $485.00
Anti-TIE1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-TIE1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

TIE1 / TIE Antibody (Internal) IHC-plus™ LS-B5201
Rabbit Polyclonal (IgG) to Human TIE1 / TIE
Human
IHC IHC-P
Unconjugated
50µl  $425.00
Anti-TIE1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Anti-TIE1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.

TIE1 / TIE Antibody (aa12-42) LS-C330693
Rabbit Polyclonal (IgG) to Human TIE1 / TIE
Mouse, Human
ELISA IHC WB
Unconjugated
200µl  $530.00

TIE1 / TIE Antibody (aa12-42, Biotin) LS-C283598
Rabbit Polyclonal (IgG) to Human TIE1 / TIE
Mouse, Human
ELISA IHC WB
Biotin Conjugated
200µl  $680.00

TIE1 / TIE Antibody (aa12-42, FITC) LS-C283600
Rabbit Polyclonal (IgG) to Human TIE1 / TIE
Mouse, Human
ELISA IHC WB
FITC Conjugated
200µl  $680.00

TIE1 / TIE Antibody (aa12-42, APC) LS-C283597
Rabbit Polyclonal (IgG) to Human TIE1 / TIE
Mouse, Human
ELISA IHC WB
APC Conjugated
200µl 0.5mg/ml  $680.00

TIE1 / TIE Antibody (aa12-42, Azide-free, HRP) LS-C283601
Rabbit Polyclonal (IgG) to Human TIE1 / TIE
Mouse, Human
ELISA IHC WB
HRP Conjugated, Azide-free
200µl  $680.00

TIE1 / TIE Antibody (aa12-42, PE) LS-C283602
Rabbit Polyclonal (IgG) to Human TIE1 / TIE
Mouse, Human
ELISA IHC WB
PE Conjugated
200µl  $680.00

TIE1 / TIE Antibody (aa12-42, AP) LS-C511702
Rabbit Polyclonal (IgG) to Human TIE1 / TIE
Mouse, Human
ELISA IHC WB
AP Conjugated
200µl  $680.00

TIE1 / TIE Antibody IHC-plus™ LS-B14395
Rabbit Polyclonal (IgG) to Human TIE1 / TIE
Rat, Human
IHC IHC-P WB
Unconjugated
50µl  $425.00
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western blot analysis of extracts of various cell lines, using TIE1 antibody.
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western blot analysis of extracts of various cell lines, using TIE1 antibody.

TIE1 / TIE Antibody LS-C671318
Rabbit Polyclonal (IgG) to Human TIE1 / TIE
Human
ELISA IF IHC IHC-P
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry image of paraffin-embedded human ovarian cancer at a dilution of 1:100
Immunofluorescent analysis of A549 cells at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Immunohistochemistry image of paraffin-embedded human ovarian cancer at a dilution of 1:100
Immunofluorescent analysis of A549 cells at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

TIE1 / TIE Antibody (C-Terminus, AP) LS-C87128
Rabbit Polyclonal to Human TIE1 / TIE
Human
ELISA IF IHC WB
AP Conjugated
100µg  $710.00

TIE1 / TIE Antibody (N-Terminus, AP) LS-C87129
Rabbit Polyclonal to Human TIE1 / TIE
Human
ELISA IF IHC WB
AP Conjugated
100µg  $710.00

TIE1 / TIE Antibody (clone 8D12B10) LS-C669138
Mouse Monoclonal [clone 8D12B10] (IgG1) to Human TIE1 / TIE
Human
ELISA IHC WB
Unconjugated
0.1mg  $365.00

TIE1 / TIE Antibody (clone 8D12D2) LS-C669143
Mouse Monoclonal [clone 8D12D2] (IgG1) to Human TIE1 / TIE
Human
ELISA IHC WB
Unconjugated
0.1mg  $365.00

TIE1 / TIE Antibody (Extracellular Domain, clone 9C1) LS-C193613
Mouse Monoclonal [clone 9C1] (IgG2a) to Human TIE1 / TIE
Human
Flo IP WB
Unconjugated
100µg 1ml  $665.00

TIE1 / TIE Antibody (aa835-1134) LS-C372463
Rabbit Polyclonal (IgG) to Mouse TIE1 / TIE
Mouse
IHC WB
Unconjugated
20µl 0.5mg/ml  $195.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $285.00; 1ml 0.5mg/ml  $485.00; 10ml 0.5mg/ml  $1,935.00
Western blot of TIE1 / TIE antibody.
Western blot of TIE1 / TIE antibody.

TIE1 / TIE Antibody (aa835-1134, HRP) LS-C706618
Rabbit Polyclonal (IgG) to Mouse TIE1 / TIE
Mouse
IHC WB
HRP Conjugated
20µl  $215.00; 100µl  $275.00; 200µl  $325.00; 1ml  $635.00; 10ml  $2,520.00
Western blot of TIE1 / TIE antibody.
Western blot of TIE1 / TIE antibody.

TIE1 / TIE Antibody (aa835-1134, Biotin) LS-C684073
Rabbit Polyclonal (IgG) to Mouse TIE1 / TIE
Mouse
IHC WB
Biotin Conjugated
20µl  $205.00; 100µl  $255.00; 200µl  $305.00; 1ml  $530.00; 10ml  $2,130.00
Western blot of TIE1 / TIE antibody.
Western blot of TIE1 / TIE antibody.

TIE1 / TIE Antibody LS-C314405
Rabbit Polyclonal (IgG) to Human TIE1 / TIE
Human
IHC WB
Unconjugated
20µl 0.5mg/ml  $185.00; 200µl 0.5mg/ml  $245.00; 1ml 0.5mg/ml  $385.00; 10ml 0.5mg/ml  $1,320.00

TIE1 / TIE Antibody (aa361-389) LS-C325726
Rabbit Polyclonal (IgG) to Mouse TIE1 / TIE
Mouse, Human
ELISA WB
Unconjugated
200µl  $530.00

TIE1 / TIE Antibody LS-C194057
Rabbit Polyclonal (IgG) to Human TIE1 / TIE
Human
IHC WB
Unconjugated
100µg 1ml  $860.00

TIE1 / TIE Antibody (aa701-898) LS-C314403
Rabbit Polyclonal (IgG) to Human TIE1 / TIE
Human
IHC WB
Unconjugated
20µl 0.5mg/ml  $185.00; 100µl 0.5mg/ml  $225.00; 200µl 0.5mg/ml  $245.00; 1ml 0.5mg/ml  $385.00; 10ml 0.5mg/ml  $1,320.00
Western blot of recombinant TIE1 / TIE.
Western blot of recombinant TIE1 / TIE.

TIE1 / TIE Antibody (clone 6F12) LS-C194821
Mouse Monoclonal [clone 6F12] (IgG1) to Human TIE1 / TIE
Human
ELISA WB
Unconjugated
100µg 100µl  $665.00

TIE1 / TIE Antibody (clone 8C9) LS-C194822
Mouse Monoclonal [clone 8C9] (IgG1) to Human TIE1 / TIE
Human
ELISA WB
Unconjugated
100µg 100µl  $665.00
Showing 1-25 of 66 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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