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Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation. Able to degrade the beta-amyloid precursor protein and generate amyloidogenic fragments.
Gene Name: | thimet oligopeptidase 1 |
Family/Subfamily: | Protease , Metallopeptidase M3 |
Synonyms: | THOP1, Endopeptidase 24.15, Endopeptidase 3.4.24.15, EP24.15, MEPD_HUMAN, Metalloendopeptidase 3.4.24.15, MP78, Thimet oligopeptidase, Thimet oligopeptidase 1, TOP |
Target Sequences: | NM_003249 NP_003240.1 P52888 |
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