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THOP1 / Thimet Oligopeptidase

thimet oligopeptidase 1

Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation. Able to degrade the beta-amyloid precursor protein and generate amyloidogenic fragments.

Gene Name: thimet oligopeptidase 1
Family/Subfamily: Protease , Metallopeptidase M3
Synonyms: THOP1, Endopeptidase 24.15, Endopeptidase 3.4.24.15, EP24.15, MEPD_HUMAN, Metalloendopeptidase 3.4.24.15, MP78, Thimet oligopeptidase, Thimet oligopeptidase 1, TOP
Target Sequences: NM_003249 NP_003240.1 P52888

Publications (2)

1
Monoclonal antibodies against the human metalloprotease EC 3.4.24.15 label neurofibrillary tangles in Alzheimer's disease brain. Conn KJ, Pietropaolo M, Ju ST, Abraham CR. Journal of neurochemistry. 1996 66:2011-8. [PubMed:8780030]
2
Mitosis-dependent protein expression in neuroblastoma cell line N1E-115. Azizi AA, Kang SU, Freilinger A, Gruber-Olipitz M, Chen WQ, Yang JW, Hengstschlger M, Slavc I, Lubec G. Journal of proteome research. 2008 7:3412-22. [PubMed:18582092]

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ELISA Kits (8)
Custom (5)
Sandwich (3)
THOP1 / Thimet Oligopeptidase (8)
Human (4)
Mouse (1)
Rat (1)
Pig (1)
96-Well Microplate (1)
96-Well Strip Plate (7)
No (8)
Plasma (2)
Serum (2)
Tissue Homogenates (2)
THOP1 / Thimet Oligopeptidase ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$783
THOP1 / Thimet Oligopeptidase ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
THOP1 / Thimet Oligopeptidase ELISA Kit
Select
Custom
96-Well Strip Plate
Pig
Colorimetric - 450nm (TMB)
1 Plate/$783
THOP1 / Thimet Oligopeptidase ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
THOP1 / Thimet Oligopeptidase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
THOP1 / Thimet Oligopeptidase ELISA Kit
Select
Custom
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
1 Plate/$672
THOP1 / Thimet Oligopeptidase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$834
THOP1 / Thimet Oligopeptidase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).