THOC7

THO Complex 7 Homolog (Drosophila)

Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.

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Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

THOC7 (5)

Publications

No (5)

Tag

GST (1)

His (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (2)

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THOC7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G109592

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

23.6 kDa

Price:

100 µg/$494

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Human THOC7 Protein (Recombinant His) - LS-G3156

Source:

E. coli

Tag:

His

Price:

50 µg/$411; 250 µg/$985; 10 µg/$276

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Human THOC7 Protein (Recombinant GST) (Full Length) - LS-G35376

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

50.1 kDa

Price:

10 µg/$479; 25 µg/$670

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Human THOC7 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68645

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

23.6 kDa

Price:

20 µg/$1,107

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Human THOC7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82691

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

23.6 kDa

Price:

20 µg/$150

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