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THNSL2 is a threonine synthase-like protein. A similar enzyme in mouse can catalyze the degradation of O-phospho-homoserine to a-ketobutyrate, phosphate, and ammonia. This protein also has phospho-lyase activity on both gamma and beta phosphorylated substrates. In mouse an alternatively spliced form of this protein has been shown to act as a cytokine and can induce the production of the inflammatory cytokine IL6 in osteoblasts. Alternate splicing results in multiple transcript variants.
Gene Name: | threonine synthase-like 2 (S. cerevisiae) |
Synonyms: | THNSL2, Threonine synthase-like 2, THS2, TSH2, SOFAT |
Target Sequences: | NM_018271 NP_060741.3 Q86YJ6 |
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