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THBS4 / Thrombospondin 4

Thrombospondin 4

Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions and is involved in various processes including cellular proliferation, migration, adhesion and attachment, inflammatory response to CNS injury, regulation of vascular inflammation and adaptive responses of the heart to pressure overload and in myocardial function and remodeling. Binds to structural extracellular matrix (ECM) proteins and modulates the ECM in response to tissue damage, contributing to cardioprotective and adaptive ECM remodeling. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors and protects myocardium from pressure overload. May contribute to spinal presynaptic hypersensitivity and neuropathic pain states after peripheral nerve injury. May play a role in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury in a NOTCH1-dependent manner.

Gene Name: Thrombospondin 4
Synonyms: THBS4, TSP4, Thrombospondin 4, Thrombospondin-4
Target Sequences: NM_003248 NP_003239.2 P35443

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Products
Proteins (5)
Recombinant (5)
THBS4 / Thrombospondin 4 (5)
No (5)
GST (1)
GST, N-terminus (1)
His-GST (3)
Human (3)
Mouse (1)
Rat (1)
E. coli (3)
Wheat Germ Extract (2)
Purified (1)
THBS4 / Thrombospondin 4 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
THBS4 / Thrombospondin 4 Protein - Recombinant Thrombospondin 4 By SDS-PAGE
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E. coli
His-GST
63.4 kDa
10 µg/$266; 50 µg/$350; 100 µg/$557; 200 µg/$697; 1 mg/$1,716; 500 µg/$1,291; 5 mg/$2,666; 2 mg/$1,893
THBS4 / Thrombospondin 4 Protein - Recombinant Thrombospondin 4 By SDS-PAGE
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E. coli
His-GST
56.4 kDa
10 µg/$279; 50 µg/$427; 100 µg/$682; 200 µg/$852; 1 mg/$1,950; 500 µg/$1,494; 5 mg/$3,409
THBS4 / Thrombospondin 4 Protein - Recombinant Thrombospondin 4 By SDS-PAGE
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E. coli
His-GST
61.0 kDa
10 µg/$283; 50 µg/$457; 100 µg/$732; 200 µg/$912; 1 mg/$2,032; 500 µg/$1,567; 5 mg/$3,193; 2 mg/$2,219
THBS4 / Thrombospondin 4 Protein - 12.5% SDS-PAGE of human THBS4 stained with Coomassie Blue
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Wheat Germ Extract
GST
132.3 kDa
2 µg/$439
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).