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THBS1 / Thrombospondin-1
thrombospondin 1
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp (By similarity). Ligand for CD36 mediating antiangiogenic properties. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors.
| Gene Name: | thrombospondin 1 |
| Synonyms: | THBS1, Thrombospondin-1, Thrombospondin-1p180, TSP, TSP1, THBS-1, THBS, Thrombospondin 1, TSP-1 |
| Target Sequences: | NM_003246 NP_003237.2 P07996 |
Publications (6)
1
Activation of the ROCK1 Branch of the Transforming Growth Factor-² Pathway Contributes to RAGE-Dependent Acceleration of Atherosclerosis in Diabetic ApoE-Null Mice. De-xiu Bu, Vivek Rai, Xiaoping Shen, Rosa Rosario, Yan Lu, Vivette D'Agati, Shi Fang Yan, Richard A. Friedman, Edem Nuglozeh and Ann Marie Schmidt. Circulation research. 2010 106:1040-51. (WB; Mouse)
[Full Text Article]
[PubMed:20133903]
[PMC:PMC2848909]
2
Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability. Schips TG, Vanhoutte D, Vo A, Correll RN, Brody MJ, Khalil H, Karch J, Tjondrokoesoemo A, Sargent MA, Maillet M, Ross RS, Molkentin JD. Nature communications. 2019 January;10:76. [Full Text Article]
[PubMed:30622267]
[PMC:PMC6325143]
Related Antibodies: LS-B4155.
3
SILAC Analysis Reveals Increased Secretion of Hemostasis-Related Factors by Senescent Cells. Wiley CD, Liu S, Limbad C, Zawadzka AM, Beck J, Demaria M, Artwood R, Alimirah F, Lopez-Dominguez JA, Kuehnemann C, Danielson SR, Basisty N, Kasler HG, Oron TR, Desprez PY, Mooney SD, Gibson BW, Schilling B, Campisi J, Kapahi P. Cell reports. 2019 September;28:3329-3337.e5. [Full Text Article]
[PubMed:31553904]
[PMC:PMC6907691]
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Products
ELISA Kits
(27)
Type
Custom
(1)
Development Kit
(1)
Sandwich
(23)
Sandwich CLIA
(2)
Target
THBS1 / Thrombospondin-1
(27)
Reactivity
Human
(10)
Mouse
(8)
Rat
(3)
Bovine
(1)
Chicken
(1)
Guinea pig
(1)
Pig
(1)
Rabbit
(1)
Product Group
DevKit DuoPlus
(1)
Format
12 x 8-Well Microstrips
(1)
96-Well Microplate
(6)
96-Well Strip Plate
(19)
Antibody Pair and Standard
(1)
Publications
No
(26)
Yes
(1)
Sample Type
Breast Milk
(1)
Cell Culture Supernatants
(4)
Cell Lysates
(2)
Plasma
(23)
Saliva
(1)
Serum
(15)
Tissue Homogenates
(9)
Sandwich
96-Well Strip Plate
Mouse
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$685
Sandwich
96-Well Microplate
Rat
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$771
Sandwich
96-Well Microplate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$795
Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$818
Sandwich
96-Well Strip Plate
Mouse
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Tissue Homogenates
1 Plate/$782
Sandwich
96-Well Strip Plate
Mouse
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Tissue Homogenates
1 Plate/$749
Sandwich
96-Well Strip Plate
Bovine
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$889
Sandwich
96-Well Microplate
Human
7.81 - 500 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Sandwich
96-Well Strip Plate
Human
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$764
Sandwich
96-Well Strip Plate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Tissue Homogenates
1 Plate/$854
Sandwich CLIA
96-Well Strip Plate
Mouse
5.49 - 4000 pg/ml
Chemiluminescent
Plasma
1 Plate/$990
Sandwich
12 x 8-Well Microstrips
Human
1563 - 100000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$618
Sandwich
96-Well Strip Plate
Chicken
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Sandwich
96-Well Strip Plate
Rabbit
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Sandwich
96-Well Strip Plate
Guinea pig
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Development Kit
Antibody Pair and Standard
Mouse
1.25 - 80 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Tissue Homogenates
500 Wells/$1,062; 1000 Wells/$1,546
Sandwich
96-Well Strip Plate
Pig
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$889
Sandwich
96-Well Strip Plate
Mouse
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Sandwich
96-Well Strip Plate
Rat
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$783
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$685
Sandwich
96-Well Strip Plate
Human
1560 - 100000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$669
Sandwich
96-Well Microplate
Mouse
39.063 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Sandwich CLIA
96-Well Strip Plate
Human
400 - 25000 pg/ml
Chemiluminescent
Cell Lysates, Plasma, Serum
1 Plate/$649
Sandwich
96-Well Strip Plate
Human
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
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