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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TH / Tyrosine Hydroxylase

tyrosine hydroxylase

Tyrosine hydroxylase in involved in the conversion of phenylalanine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines and as such has a key role in the physiology of adrenergic neurons. TH is encoded by four distinct mRNAs produced by alternative splicing of a single primary transcript. Expression of the mRNAs varies in different parts of the nervous system. Defects in TH are the cause of autosomal recessive Segawa syndrome.

Gene Name: tyrosine hydroxylase
Family/Subfamily: Monooxygenase
Synonyms: TH, DYT14, Dystonia 14, TYH, Tyrosine 3-hydroxylase, Tyrosine hydroxylase, DYT5b, Tyrosine 3-monooxygenase
Target Sequences: NM_000360 NP_000351.2 P07101

Filtered By: None
Target
TH / Tyrosine Hydroxylase (196)
Reactivity
Human (120)
Mouse (96)
Rat (158)
Bat (9)
Bovine (21)
Cat (7)
Chicken (18)
Cow (8)
Dog (13)
Drosophila (7)
Ferret (7)
Frog (1)
Guinea pig (9)
Hamster (1)
Mammal (10)
Monkey (6)
Pig (8)
Rabbit (15)
Xenopus (9)
Zebrafish (9)
Application
IHC (135)
IHC-Fr (12)
IHC-P (33)
WB (177)
Flo (3)
ELISA (29)
ICC (31)
IF (58)
IP (24)
Peptide-ELISA (9)
Host
rabbit (150)
mouse (29)
goat (1)
chicken (5)
sheep (11)
Isotype
IgG (112)
IgG1 (14)
IgG1,k (1)
IgG2a (9)
IgG2a,k (1)
IgG2b (2)
IgM (1)
IgY (3)
Clonality
monoclonal mc (30)
polyclonal pc (166)
Clone
185 (1)
1A10 (1)
1A12 (1)
1A4 (1)
1B8D2 (1)
1D8 (1)
2D4 (1)
2E5 (1)
2E6 (1)
3A7 (1)
3G3 (1)
3H3 (1)
EP1532Y (1)
TH-100 (3)
TOH A1.1 (1)
TS106 (1)
Format
AP Conjugated (8)
APC (3)
APC Conjugated (10)
Biotin Conjugated (16)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (17)
HRP Conjugated (14)
Magnetic beads Conjugated (1)
PE Conjugated (11)
Sepharose Conjugated (1)
Unconjugated (112)
Epitope
pSer19 (16)
pSer40 (16)
pSer31 (14)
N-Terminus (10)
aa45-214 (10)
aa82-310 (10)
aa34-301 (9)
10-90 aa (6)
C-Terminus (5)
aa35-84 (4)
1-80 aa (2)
pSer71 (2)
Gln25 (1)
Gly13 (1)
Phe34 (1)
Pro2 (1)
Ser40 (1)
aa1-20 (1)
aa1-50 (1)
aa10-59 (1)
aa193-222 (1)
aa29-33 (1)
aa41-90 (1)
aa5-54 (1)
aa513-524 (1)
aa63-78 (1)
pSer62 (1)
pSer8 (1)
Publications
No (196)
Showing 1-25 of 196 results

TH / Tyrosine Hydroxylase Antibody (C-Terminus, clone EP1532Y) IHC-plus™ LS-B8480
Rabbit Monoclonal [clone EP1532Y] (IgG) to Human TH / Tyrosine Hydroxylase
Mouse, Rat, Human
Flo ICC IHC IHC-P WB
Unconjugated
50µl  $425.00
Anti-TH / Tyrosine Hydroxylase antibody IHC of human adrenal medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50-1:100.
Western blot analysis on PC-12 cell lysate using anti-Tyrosine 3-Hydroxylase antibody, dilution 1:100000.
Anti-TH / Tyrosine Hydroxylase antibody IHC of human adrenal medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50-1:100.
Western blot analysis on PC-12 cell lysate using anti-Tyrosine 3-Hydroxylase antibody, dilution 1:100000.

TH / Tyrosine Hydroxylase Antibody IHC-plus™ LS-B3443
Rabbit Polyclonal (IgG) to Rat TH / Tyrosine Hydroxylase
Mouse, Rat, Cat, Ferret, Human
ELISA IF IHC IHC-Fr IHC-P IP WB
Unconjugated
50µl  $485.00
Anti-TH / Tyrosine Hydroxylase antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Anti-TH / Tyrosine Hydroxylase antibody IHC of human prostate, nerve. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Anti-TH / Tyrosine Hydroxylase antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Anti-TH / Tyrosine Hydroxylase antibody IHC of human prostate, nerve. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.

TH / Tyrosine Hydroxylase Antibody (phospho-Ser40) IHC-plus™ LS-B2462
Rabbit Polyclonal to Rat TH / Tyrosine Hydroxylase
Rat, Human
IF IHC IHC-Fr IHC-P WB
Unconjugated
50µl  $425.00
Anti-TH / Tyrosine Hydroxylase antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Western blot of recombinant phospho- and dephospho-TH showing selective immunolabeling by the phospho-specific antibody of the ~60k TH phosphorylated at Ser40.
Anti-TH / Tyrosine Hydroxylase antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Western blot of recombinant phospho- and dephospho-TH showing selective immunolabeling by the phospho-specific antibody of the ~60k TH phosphorylated at Ser40.

TH / Tyrosine Hydroxylase Antibody (clone 1D8) IHC-plus™ LS-B12072
Mouse Monoclonal [clone 1D8] (IgG1) to Human TH / Tyrosine Hydroxylase
Human
IF IHC IHC-P WB
Unconjugated
50µl 1mg/ml  $425.00
Human Prostate, Nerve: Formalin-Fixed, Paraffin-Embedded (FFPE)
Anti-TH mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY TH.
Human Prostate, Nerve: Formalin-Fixed, Paraffin-Embedded (FFPE)
Anti-TH mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY TH.

TH / Tyrosine Hydroxylase Antibody IHC-plus™ LS-B2873
Rabbit Polyclonal to Rat TH / Tyrosine Hydroxylase
Rat, Human
IF IHC IHC-Fr IHC-P WB
Unconjugated
50µl  $425.00
Anti-TH / Tyrosine Hydroxylase antibody IHC of human heart, nerve. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Western blot of 10 ug of rat caudate lysate showing specific immunolabeling of the ~60k TH protein.
Anti-TH / Tyrosine Hydroxylase antibody IHC of human heart, nerve. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Western blot of 10 ug of rat caudate lysate showing specific immunolabeling of the ~60k TH protein.

TH / Tyrosine Hydroxylase Antibody (N-Terminus) LS-C153588
Rabbit Polyclonal to Drosophila TH / Tyrosine Hydroxylase
Drosophila
ELISA WB
Unconjugated
100µg 100µl 1mg/ml  $345.00

TH / Tyrosine Hydroxylase Antibody IHC-plus™ LS-B9914
Sheep Polyclonal to Rat TH / Tyrosine Hydroxylase
Rat, Human
IF IHC IHC-Fr IHC-P WB
Unconjugated
100µl  $485.00
Anti-TH / Tyrosine Hydroxylase antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Western blot of rat caudate lysate showing specific immunolabeling of the ~60k Tyrosine Hydroxylase protein.
Anti-TH / Tyrosine Hydroxylase antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Western blot of rat caudate lysate showing specific immunolabeling of the ~60k Tyrosine Hydroxylase protein.

TH / Tyrosine Hydroxylase Antibody (aa41-90) IHC-plus™ LS-B5365
Rabbit Polyclonal (IgG) to Human TH / Tyrosine Hydroxylase
Mouse, Rat, Human
IF IHC IHC-P Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-TH / Tyrosine Hydroxylase antibody IHC of human adrenal medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Immunofluorescence analysis of HUVEC cells, using Tyrosine Hydroxylase Antibody. The picture on the right is blocked with the synthesized peptide.
Anti-TH / Tyrosine Hydroxylase antibody IHC of human adrenal medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Immunofluorescence analysis of HUVEC cells, using Tyrosine Hydroxylase Antibody. The picture on the right is blocked with the synthesized peptide.

TH / Tyrosine Hydroxylase Antibody LS-C40054
Mouse Monoclonal (IgG2a) to Rat TH / Tyrosine Hydroxylase
Chicken, Bovine, Rat
IHC WB
Unconjugated
40µg 1mg/ml  $710.00

TH / Tyrosine Hydroxylase Antibody (N-Terminus) LS-C354110
Rabbit Polyclonal to Human TH / Tyrosine Hydroxylase
Mouse, Dog, Bovine, Rat, Human
ICC IF IHC IHC-P IP WB
Unconjugated
100µl 1mg/ml  $245.00
Immunohistochemical analysis of Tyrosine Hydroxylase staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of Tyrosine Hydroxylase staining in DLD cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
Immunohistochemical analysis of Tyrosine Hydroxylase staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of Tyrosine Hydroxylase staining in DLD cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).

TH / Tyrosine Hydroxylase Antibody (clone TS106) LS-C191418
Mouse Monoclonal [clone TS106] (IgG1) to Rat TH / Tyrosine Hydroxylase
Rat
ELISA ICC IF IHC
Unconjugated
250µl  $635.00

TH / Tyrosine Hydroxylase Antibody LS-C122516
Mouse Monoclonal (IgG1) to Rat TH / Tyrosine Hydroxylase
Rabbit, Rat, Human
IHC IHC-Fr IHC-P WB
Unconjugated
100µg 1000µl  $530.00

TH / Tyrosine Hydroxylase Antibody (clone TH-100) LS-C171011
Mouse Monoclonal [clone TH-100] (IgG1) to Rat TH / Tyrosine Hydroxylase
Rabbit, Rat, Human
IHC IHC-Fr IHC-P WB
Unconjugated
100µg 1ml 1mg/ml  $295.00

TH / Tyrosine Hydroxylase Antibody LS-C40029
Rabbit Polyclonal (IgG) to Rat TH / Tyrosine Hydroxylase
Rat
IF IHC WB
Unconjugated
100µl  $515.00

TH / Tyrosine Hydroxylase Antibody (clone 1B8D2) LS-C682382
Mouse Monoclonal [clone 1B8D2] (IgG1) to Human TH / Tyrosine Hydroxylase
Human
ELISA Flo ICC IHC WB
Unconjugated
100µl  $365.00
Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using TH mouse mAb with DAB staining.
Immunofluorescence analysis of Hela cells using TH mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher
Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using TH mouse mAb with DAB staining.
Immunofluorescence analysis of Hela cells using TH mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher

TH / Tyrosine Hydroxylase Antibody (N-Terminus) LS-C40057
Mouse Monoclonal (IgG1,k) to Rat TH / Tyrosine Hydroxylase
Frog, Rat, Human, Monkey
IHC WB
Unconjugated
100µl  $650.00

TH / Tyrosine Hydroxylase Antibody (aa63-78) LS-C124748
Rabbit Polyclonal to Human TH / Tyrosine Hydroxylase
Rat, Human
IHC
Unconjugated
100µl  $590.00

TH / Tyrosine Hydroxylase Antibody (C-Terminus) LS-C121308
Rabbit Polyclonal (IgG) to Mouse TH / Tyrosine Hydroxylase
Mouse
WB
Unconjugated
100µg 1mg/ml  $665.00

TH / Tyrosine Hydroxylase Antibody (N-Terminus) LS-C354112
Rabbit Polyclonal to Human TH / Tyrosine Hydroxylase
Chicken, Mouse, Dog, Rat, Human
ICC IF IHC IHC-P WB
Unconjugated
100µl 1mg/ml  $245.00
Immunohistochemical analysis of Tyrosine Hydroxylase staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of Tyrosine Hydroxylase staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
Immunohistochemical analysis of Tyrosine Hydroxylase staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of Tyrosine Hydroxylase staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).

TH / Tyrosine Hydroxylase Antibody (phospho-Ser19) LS-C358879
Rabbit Polyclonal to Human TH / Tyrosine Hydroxylase
Mouse, Dog, Bovine, Rat, Human
ICC IF IHC IHC-P WB
Unconjugated
30µl 1mg/ml  $215.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $325.00
Immunohistochemical analysis of Tyrosine Hydroxylase (pS19) staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of Tyrosine Hydroxylase (pS19) staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
Immunohistochemical analysis of Tyrosine Hydroxylase (pS19) staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Immunofluorescent analysis of Tyrosine Hydroxylase (pS19) staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).

TH / Tyrosine Hydroxylase Antibody (phospho-Ser31) LS-C40040
Rabbit Polyclonal to Human TH / Tyrosine Hydroxylase
Mouse, Rat, Human
Flo IF IHC IHC-Fr WB
Unconjugated
100µl  $890.00

TH / Tyrosine Hydroxylase Antibody (phospho-Ser19) LS-C416494
Rabbit Polyclonal to Human TH / Tyrosine Hydroxylase
Mouse, Rat, Human
ICC IF IHC WB
Unconjugated
100µg 1mg/ml  $305.00
Western blot of Tyrosine Hydroxylase phosphorylation expression in PC12 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
Western blot of Tyrosine Hydroxylase phosphorylation expression in PC12 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

TH / Tyrosine Hydroxylase Antibody (phospho-Ser19) LS-C416497
Rabbit Polyclonal to Human TH / Tyrosine Hydroxylase
Mouse, Rat, Human
ICC IF IHC WB
Unconjugated
100µg 1mg/ml  $305.00
Western blot of Tyrosine Hydroxylase phosphorylation expression in Insulin treated 293 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
Western blot of Tyrosine Hydroxylase phosphorylation expression in Insulin treated 293 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

TH / Tyrosine Hydroxylase Antibody (aa10-59) LS-C117545
Rabbit Polyclonal (IgG) to Human TH / Tyrosine Hydroxylase
Mouse, Rat, Human
IF IHC IHC-P Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Tyrosine Hydroxylase Antibody. The picture on the right is blocked with the synthesized peptide.
Immunofluorescence analysis of HUVEC cells, using Tyrosine Hydroxylase Antibody. The picture on the right is blocked with the synthesized peptide.
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Tyrosine Hydroxylase Antibody. The picture on the right is blocked with the synthesized peptide.
Immunofluorescence analysis of HUVEC cells, using Tyrosine Hydroxylase Antibody. The picture on the right is blocked with the synthesized peptide.

TH / Tyrosine Hydroxylase Antibody (phospho-Ser19) LS-C199701
Rabbit Polyclonal (IgG) to Human TH / Tyrosine Hydroxylase
Mouse, Rat, Human
IF IHC IHC-P Peptide-ELISA WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Immunohistochemistry analysis of paraffin-embedded human brain, using Tyrosine Hydroxylase (Phospho-Ser19) Antibody. The picture on the right is blocked with the phospho peptide.
Immunofluorescence analysis of HUVEC cells, using Tyrosine Hydroxylase (Phospho-Ser19) Antibody. The picture on the right is blocked with the phospho peptide.
Immunohistochemistry analysis of paraffin-embedded human brain, using Tyrosine Hydroxylase (Phospho-Ser19) Antibody. The picture on the right is blocked with the phospho peptide.
Immunofluorescence analysis of HUVEC cells, using Tyrosine Hydroxylase (Phospho-Ser19) Antibody. The picture on the right is blocked with the phospho peptide.
Showing 1-25 of 196 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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