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TGN46 / TGN38

trans-golgi network protein 2

May be involved in regulating membrane traffic to and from trans-Golgi network.Enzyme and pathway databases Reactome - a knowledgebase of biological pathways and processes<br/><a href='/database/88'>More..</a>ReactomeiREACT_19400. Golgi Associated Vesicle Biogenesis. <p>Provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.</p><p><a href='../manual/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi<p>Provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.</p><p><a href='../manual/protein_names' target='_top'>More...</a></p>Protein namesiRecommended name:Trans-Golgi network integral membrane protein 2Alternative name(s):TGN38 homologTGN46TGN48Trans-Golgi network protein TGN51<p>Indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. 4 distinct tokens exist: [Character 2018]Name', [Character 2018]Synonyms', [Character 2018]Ordered locus names' and [Character 2018]ORF names'.</p><p><a href='../manual/gene_name' target='_top'>More...</a></p>Gene namesiName:TGOLN2Synonyms:TGN46, TGN51

Gene Name: trans-golgi network protein 2
Synonyms: TGOLN2, TGN38, TGN38 homolog, TGN46, TGN48, TGN51, TTGN2, Trans-golgi network protein 2
Target Sequences: NM_006464 NP_006455.2 O43493

Publications (3)

1
ATP7A gene addition to the choroid plexus results in long-term rescue of the lethal copper transport defect in a Menkes disease mouse model. Donsante A, Yi L, Zerfas PM, Brinster LR, Sullivan P, Goldstein DS, Prohaska J, Centeno JA, Rushing E, Kaler SG. Molecular therapy : the journal of the American Society of Gene Therapy. 2011 19:2114-23. (ICC; Human) [PubMed:21878905] [PMC:PMC3242653]
2
CutA divalent cation tolerance homolog (Escherichia coli) (CUTA) regulates -cleavage of -amyloid precursor protein (APP) through interacting with -site APP cleaving protein 1 (BACE1). Zhao Y, Wang Y, Hu J, Zhang X, Zhang YW. The Journal of biological chemistry. 2012 287:11141-50. (WB; Human) [PubMed:22351782] [PMC:PMC3322838]
3
Hypomorphism for RPGRIP1L, a ciliary gene vicinal to the FTO locus, causes increased adiposity in mice. Stratigopoulos G, Martin Carli JF, O'Day DR, Wang L, Leduc CA, Lanzano P, Chung WK, Rosenbaum M, Egli D, Doherty DA, Leibel RL. Cell metabolism. 2014 19:767-79. (WB; Rat) [Full Text Article] [PubMed:24807221] [PMC:PMC4131684] Related Antibodies: LS-C124646.

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Proteins (8)
Over-Expression Lysate (2)
Recombinant (6)
TGN46 / TGN38 (8)
No (8)
6His, C-terminus (2)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (7)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Human Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (2)
Purified (1)
Low endotoxin level (2)
TGN46 / TGN38 Protein - Purified recombinant protein TGOLN2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
45.7 kDa
20 µg/$1,107
TGN46 / TGN38 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
38.3kD
10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353
TGN46 / TGN38 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
45.7 kDa
20 µg/$150
TGN46 / TGN38 Protein - 12.5% SDS-PAGE of human TGOLN2 stained with Coomassie Blue
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Wheat Germ Extract
GST
73.5 kDa
2 µg/$439
TGN46 / TGN38 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
45.7 kDa
100 µg/$494
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
38.3 kDa
10 µg/$317; 50 µg/$524
TGN46 / TGN38 Protein - Recombinant Trans Golgi Network Protein 2 (TGOLN2) by SDS-PAGE
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E. coli
None
34.7kDa
10 µg/$267; 50 µg/$352; 200 µg/$702; 100 µg/$562; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).