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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TGM2 / Transglutaminase 2

transglutaminase 2

Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: transglutaminase 2
Synonyms: TGM2, G-ALPHA-h, GNAH, TG(C), Transglutaminase 2, Transglutaminase C, TG2, TGase H, TGase-2, TGase-H, Transglutaminase H, TGase C, TGC, TTG, C polypeptide, Tgase II, Tissue transglutaminase, Transglutaminase-2
Target Sequences: NM_004613 NP_004604.2 P21980

Filtered by: None
Target
TGM2 / Transglutaminase 2 (107)
Reactivity
Human (105)
Mouse (45)
Rat (36)
Chimpanzee (6)
Dog (14)
Gibbon (6)
Guinea pig (23)
Horse (4)
Monkey (12)
Rabbit (18)
Application
IHC (70)
IHC-Fr (2)
IHC-P (30)
WB (96)
Flo (5)
Block (2)
ELISA (22)
ICC (3)
IF (18)
IP (34)
Peptide-ELISA (4)
Host
rabbit (66)
mouse (37)
goat (4)
Isotype
IgG (42)
IgG,k (1)
IgG1 (15)
IgG1,k (11)
IgG2a,k (6)
IgG3 (1)
IgG3,k (2)
Clonality
monoclonal mc (38)
polyclonal pc (69)
Clone
2A1 (1)
2F4 (1)
3H2B8 (1)
7D2 (3)
CUB 7402 (3)
CUB7402 (1)
EP2957 (1)
OTI1A3 (2)
OTI1C4 (2)
OTI2F9 (2)
OTI4H5 (2)
SPM592 (2)
TGM2/419 (3)
Format
AP Conjugated (3)
APC (1)
APC Conjugated (4)
Azide-free (4)
Biotin Conjugated (10)
Carrier-free (4)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (7)
HRP Conjugated (7)
PE Conjugated (4)
Ready-to-Use (1)
Unconjugated (70)
Epitope
aa1-687 (8)
N-Terminus (5)
aa431-480 (4)
aa438-687 (2)
1-80 aa, N-terminal (1)
Asp11 (1)
Internal (1)
Lys444 (1)
Thr428 (1)
aa1-50 (1)
aa399-418 (1)
aa550-600 (1)
aa578-591 (1)
aa600-650 (1)
aa625-675 (1)
aa667-680 (1)
aa669-681 (1)
aa7-34 (1)
Publications
No (107)
Showing 1-25 of 107 results

IHC-plus™ TGM2 / Transglutaminase 2 Antibody (clone 2A1) LS-B2599
Mouse Monoclonal [clone 2A1] (IgG,k) to Human TGM2 / Transglutaminase 2
Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-TGM2 / Transglutaminase 2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Western blot Image

IHC-plus™ TGM2 / Transglutaminase 2 Antibody LS-B2235
Rabbit Polyclonal (IgG) to Human TGM2 / Transglutaminase 2
Mouse, Rat, Human
IHC, IHC-P, IP, WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-TGM2 / Transglutaminase 2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

IHC-plus™ TGM2 / Transglutaminase 2 Antibody (Azide-free) LS-B2681
Rabbit Polyclonal (IgG) to Human TGM2 / Transglutaminase 2
Mouse, Rat, Human
IHC, IHC-P, IP, WB
Unconjugated, Azide-free
50µl 1mg/ml  $425.00
Anti-TGM2 / Transglutaminase 2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unmodified form of this product. Other forms have not been tested.

IHC-plus™ TGM2 / Transglutaminase 2 Antibody (aa431-480) LS-B5802
Rabbit Polyclonal (IgG) to Human TGM2 / Transglutaminase 2
Rabbit, Mouse, Rat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100µl  $485.00
Anti-TGM2 / Transglutaminase 2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HepG2 cell lysate. Antibody concentration: 0.25 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TGM2 / Transglutaminase 2 Antibody (clone CUB 7402, Azide-free) LS-C87956
Mouse Monoclonal [clone CUB 7402] (IgG1,k) to Guinea pig TGM2 / Transglutaminase 2
Rabbit, Dog, Guinea pig, Human
Block, IF, IHC, IHC-P, IP, WB
Unconjugated, Azide-free
100µl 1mg/ml  $710.00; 200µl 1mg/ml  $1,170.00
Formalin-fixed, paraffin-embedded human breast carcinoma stained with peroxidase-conjugate and DAB chromogen. Note cell membrane and cytoplasmic staining of tumor and endothelial cells. This image was taken for the unmodified form of this product. Other forms have not been tested.

TGM2 / Transglutaminase 2 Antibody (aa600-650) LS-C148365
Rabbit Polyclonal to Human TGM2 / Transglutaminase 2
Human
IHC, IHC-P, WB
Unconjugated
100µg 0.5mg/ml  $335.00
Western blot of Transglutaminase 2inA) MCF-7 negative control cell lysate and B) BxPC-3 cell lysate using Peptide-affinity Purified Polyclonal Antibody to Transglutaminase 2 (TG2) at0.64 ug/ml.

TGM2 / Transglutaminase 2 Antibody (aa578-591) LS-C154877
Goat Polyclonal to Human TGM2 / Transglutaminase 2
Mouse, Rat
Peptide-ELISA, WB
Unconjugated
100µg 0.5mg/ml  $405.00
TGM2 antibody (1 ug/ml) staining of Mouse Kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

IHC-plus™ TGM2 / Transglutaminase 2 Antibody LS-B5175
Rabbit Polyclonal (IgG) to Human TGM2 / Transglutaminase 2
Mouse, Rat, Human
IHC, IHC-P, IP, WB
Unconjugated
50µg 1mg/ml  $425.00
Anti-TGM2 / Transglutaminase 2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

TGM2 / Transglutaminase 2 Antibody LS-C62258
Rabbit Polyclonal (IgG) to Human TGM2 / Transglutaminase 2
Human
IP, WB
Unconjugated
100µl  $305.00
Western blot Image

TGM2 / Transglutaminase 2 Antibody (clone CUB7402) LS-C95548
Mouse Monoclonal [clone CUB7402] (IgG1) to Guinea pig TGM2 / Transglutaminase 2
Guinea pig, Human
IHC
Unconjugated
0.5ml  $425.00; 1ml  $665.00
Formalin-fixed, paraffin-embedded human breast carcinoma stained with Transglutaminase II antibody.

IHC-plus™ TGM2 / Transglutaminase 2 Antibody (Internal, clone EP2957) LS-B7375
Rabbit Monoclonal [clone EP2957] to Human TGM2 / Transglutaminase 2
Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
50µl  $425.00
Anti-Transglutaminase 2 / TGM2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
Western blot analysis on (A) U87-MG, (B) A549, and (C) HUVEC cell lysates using anti-Transglutaminase 2 antibody.

TGM2 / Transglutaminase 2 Antibody (Lys444) LS-C97227
Rabbit Polyclonal to Human TGM2 / Transglutaminase 2
Human
IF, IHC, IHC-P, WB
Unconjugated
400µl  $325.00
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with *TGM2 antibody (Center K444), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Fluorescent confocal image of U251 cell stained with TGM2 Antibody (Center K444). U251 cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with TGM2 primary antibody (1:25, 1 h at 37°C). For secondary antibody, Alexa Fluor 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37°C). Cytoplasmic actin was counterstained with Alexa Fluor 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37°C). Nuclei were counterstained with DAPI (blue) (10 ug/ml, 10 min). TGM2 immunoreactivity is localized to Cytoplasm significantly.

TGM2 / Transglutaminase 2 Antibody (clone CUB 7402, Biotin) LS-C87955
Mouse Monoclonal [clone CUB 7402] (IgG1,k) to Guinea pig TGM2 / Transglutaminase 2
Rabbit, Dog, Guinea pig, Human
Block, IF, IHC, IHC-P, IP, WB
Biotin Conjugated
100µl 200µg/ml  $365.00; 500µl 200µg/ml  $845.00; 1ml 200µg/ml  $1,335.00

IHC-plus™ TGM2 / Transglutaminase 2 Antibody (clone CUB 7402) LS-B8560
Mouse Monoclonal [clone CUB 7402] (IgG1,k) to Guinea pig TGM2 / Transglutaminase 2
Rabbit, Dog, Guinea pig, Human
IF, IHC, IHC-P, IP, WB
Unconjugated
250µl  $485.00
Anti-Transglutaminase 2 / TGM2 antibody IHC of human prostate, epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.

TGM2 / Transglutaminase 2 Antibody (clone 2F4) LS-C133481
Mouse Monoclonal [clone 2F4] (IgG2a,k) to Human TGM2 / Transglutaminase 2
Human
ELISA, IF, WB
Unconjugated
100µg  $365.00
Immunofluorescence of monoclonal antibody to TGM2 on HeLa cell. [antibody concentration 10 ug/ml].
Western blot of TGM2 expression in transfected 293T cell line by TGM2 monoclonal antibody (M10), clone 2F4.

TGM2 / Transglutaminase 2 Antibody (Biotin) LS-C88594
Rabbit Polyclonal (IgG) to Human TGM2 / Transglutaminase 2
Mouse, Rat, Human
IHC, IHC-P, IP, WB
Biotin Conjugated
0.1ml  $315.00; 0.5ml  $530.00; 1ml  $815.00

TGM2 / Transglutaminase 2 Antibody LS-C489419
Rabbit Polyclonal to Human TGM2 / Transglutaminase 2
Human
ELISA, IP, WB
Unconjugated
50µl  $255.00; 100µl  $305.00; 200µl  $355.00

TGM2 / Transglutaminase 2 Antibody (aa625-675) LS-C290869
Rabbit Polyclonal (IgG) to Human TGM2 / Transglutaminase 2
Human
IP, WB
Unconjugated
100µl 1mg/ml  $395.00
Detection of Human TG2 by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa and 293T cells. Antibodies: Affinity purified rabbit anti-TG2 antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

TGM2 / Transglutaminase 2 Antibody (clone TGM2/419) LS-C391044
Mouse Monoclonal [clone TGM2/419] (IgG2a,k) to Human TGM2 / Transglutaminase 2
Rabbit, Mouse, Rat, Human, Monkey
Flo, IF, IHC, IHC-P
Unconjugated
20µg 0.2mg/ml  $295.00; 100µg 0.2mg/ml  $465.00
Formalin-fixed, paraffin-embedded human tonsil stained with Transglutaminase 2 antibody (TGM2/419).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Formalin-fixed, paraffin-embedded human placenta stained with Transglutaminase 2 antibody.  This image was taken for the unmodified form of this product. Other forms have not been tested.

TGM2 / Transglutaminase 2 Antibody (clone TGM2/419, Azide-free) LS-C391041
Mouse Monoclonal [clone TGM2/419] (IgG2a,k) to Human TGM2 / Transglutaminase 2
Rabbit, Mouse, Rat, Human, Monkey
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free
100µg 1mg/ml  $465.00
Formalin-fixed, paraffin-embedded human tonsil stained with Transglutaminase 2 antibody (TGM2/419).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Formalin-fixed, paraffin-embedded human placenta stained with Transglutaminase 2 antibody.  This image was taken for the unmodified form of this product. Other forms have not been tested.

TGM2 / Transglutaminase 2 Antibody (clone TGM2/419, Ready-to-Use) LS-C391042
Mouse Monoclonal [clone TGM2/419] (IgG2a,k) to Human TGM2 / Transglutaminase 2
Rabbit, Mouse, Rat, Human, Monkey
Flo, IF, IHC, IHC-P
Unconjugated, Ready-to-Use
7ml  $465.00
Formalin-fixed, paraffin-embedded human tonsil stained with Transglutaminase 2 antibody (TGM2/419).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Formalin-fixed, paraffin-embedded human placenta stained with Transglutaminase 2 antibody.  This image was taken for the unmodified form of this product. Other forms have not been tested.

TGM2 / Transglutaminase 2 Antibody (HRP) LS-C318043
Rabbit Polyclonal (IgG) to Human TGM2 / Transglutaminase 2
Human
ELISA, WB
HRP Conjugated
50µg 0.42mg/ml  $285.00; 100µg  $385.00
Western blot of Protein-glutamine gamma-glutamyltransferase 2 antibody at 2 ug/ml with HepG2 whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:10000 dilution. Predicted band size: 77.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

IHC-plus™ TGM2 / Transglutaminase 2 Antibody (aa1-50) LS-B12446
Rabbit Polyclonal (IgG) to Human TGM2 / Transglutaminase 2
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100µl 1mg/ml  $505.00
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western blot analysis of lysates from HUVEC cells, using Transglutaminase 2 Antibody. The lane on the right is blocked with the synthesized peptide.

IHC-plus™ TGM2 / Transglutaminase 2 Antibody (aa667-680) LS-B12812
Goat Polyclonal to Human TGM2 / Transglutaminase 2
Dog, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µg 0.5mg/ml  $425.00
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Antibody (0.03 ug/ml) staining of Human Lung lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

TGM2 / Transglutaminase 2 Antibody LS-C489420
Rabbit Polyclonal to Human TGM2 / Transglutaminase 2
Human
ELISA
Unconjugated
50µl  $275.00; 100µl  $355.00
Showing 1-25 of 107 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).