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TGFBI

transforming growth factor, beta-induced, 68kDa

TGFBI is an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy.

Gene Name: transforming growth factor, beta-induced, 68kDa
Family/Subfamily: TGF beta , not assigned-TGF beta
Synonyms: TGFBI, BIGH3, Beta ig-h3, CDG2, CSD, CSD2, CSD3, CDGG1, EBMD, Kerato-epithelin, LCD1, RGD-CAP, CDB1, CSD1
Target Sequences: NM_000358 NP_000349.1 Q15582

Publications (2)

1
Target proteomic profiling of frozen pancreatic CD24+ adenocarcinoma tissues by immuno-laser capture microdissection and nano-LC-MS/MS. Zhu J, Nie S, Wu J, Lubman DM. Journal of proteome research. 2013 12:2791-804. (WB; Human) [Full Text Article] [PubMed:23679566] [PMC:PMC3726273] Related Antibodies: LS-B5942.
2
Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer. Sidharth V Puram, Itay Tirosh, Anuraag S Parikh, Anoop P Patel, Keren Yizhak, Shawn Gillespie, Christopher Rodman, Christina L Luo, Edmund A Mroz, Kevin S Emerick, Daniel G Deschler, Mark A Varvares, Ravi Mylvaganam, Orit Rozenblatt-Rosen, James W Rocco, William C Faquin, Derrick T Lin, Aviv Regev, Bradley E Bernstein. Cell. 2017 Dec;171:1611-1624e24. [Full Text Article] [PubMed:29198524] [PMC:PMC5878932] Related Antibodies: LS-C325695.

☰ Filters
Products
Proteins (9)
Over-Expression Lysate (2)
Recombinant (7)
TGFBI (9)
No (9)
GST, N-terminus (1)
His (1)
His, N-Terminal (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (7)
Mouse (1)
293T Cells (1)
E. coli (4)
HEK 293 Cells (2)
Human Cells (1)
Wheat Germ Extract (1)
Purified (1)
Low endotoxin level (2)
TGFBI Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
TGFBI Protein - Purified recombinant protein TGFBI was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
72.4 kDa
20 µg/$1,107
TGFBI Protein - Recombinant Transforming Growth Factor Beta Induced Protein By SDS-PAGE
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E. coli
His, N-Terminal
26.9 kDa
10 µg/$283; 50 µg/$457; 100 µg/$732; 200 µg/$912; 1 mg/$2,032; 500 µg/$1,567; 5 mg/$3,193; 2 mg/$2,219
TGFBI Protein - Recombinant Transforming Growth Factor Beta Induced Protein By SDS-PAGE
Select
E. coli
His-T7
26.9 kDa
10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090
TGFBI Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
74.68 kDa
100 µg/$494
TGFBI Protein
Select
E. coli
None
100 µg/$361; 500 µg/$739; 20 µg/$261
TGFBI Protein
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
100 µg/$317; 500 µg/$526; 20 µg/$245
Select
293T Cells
Myc-DDK (Flag)
74.68 kDa
20 µg/$150
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
74 kDa
100 µg/$721
Viewing 1-9 of 9 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).