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TGFB3 / TGF Beta3

transforming growth factor, beta 3

Transforming growth factor beta 3 is a cytokine involved in cell differentiation, embryogenesis and development. It belongs to a large family of cytokines called the Transforming growth factor beta superfamily, which includes the TGF-beta family, Bone morphogenetic proteins (BMPs), growth and differentiation factors (GDFs), inhibins and activins. TGFB3 is believed to regulate molecules involved in cellular adhesion and extracellular matrix (ECM) formation during the process of palate development.

Gene Name: transforming growth factor, beta 3
Family/Subfamily: TGF beta , not assigned-TGF beta
Synonyms: TGFB3, ARVD, TGF Beta 3, TGF-beta-3, TGF-beta3
Target Sequences: NM_003239 NP_003230.1 P10600

Publications (1)

1
Circulating extracellular vesicle-associated TGFß3 modulates response to cytotoxic therapy in head and neck squamous cell carcinoma. Dorival Mendes Rodrigues-Junior, Soon Sim Tan, Sai Kiang Lim, Hui Sun Leong, Matias Eliseo Melendez, Cintia Regina Niederauer Ramos, Luciano de Souza Viana, Daniel S W Tan, Andre Lopes Carvalho, N Gopalakrishna Iyer, Andre Luiz Vettore. Carcinogenesis. 2019 December;40:1452-1461. [Full Text Article] [PubMed:31436806]

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).