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TFF2 / SP

trefoil factor 2

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. The encoded protein inhibits gastric acid secretion. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.

Gene Name: trefoil factor 2
Synonyms: TFF2, SP, Spasmolysin, Trefoil factor 2, SML1, Spasmolytic polypeptide, Spasmolytic protein 1
Target Sequences: BC032820 AAH32820.1 Q03403

Publications (1)

1
Trefoil factor 2 secreted from damaged hepatocytes activates hepatic stellate cells to induce fibrogenesis. Bichen Zhang, Kalina Lapenta, Qi Wang, Jin Hyun Nam, Dongjun Chung, Marie E Robert, Michael H Nathanson, Xiaoyong Yang. The Journal of biological chemistry. 2021 June;297:100887. [Full Text Article] [PubMed:34146542] [PMC:PMC8267550] Related Antibodies: LS-C296796.

☰ Filters
Products
Proteins (17)
Over-Expression Lysate (2)
Recombinant (15)
TFF2 / SP (17)
No (17)
6His, C-terminus (3)
6His, N-terminus (1)
6His, N-terminus + Mouse IgG Fc, C-terminus (1)
GST (1)
His (3)
His,C-terminus (1)
Myc-DDK (Flag) (3)
Human (10)
Mouse (5)
Rat (1)
293T Cells (1)
E. coli (8)
HEK 293 Cells (3)
Human Cells (1)
Mammalian Cells (3)
Wheat Germ Extract (1)
Purified (4)
Low endotoxin level (6)
Biologically active (3)
TFF2 / SP Protein - Purified recombinant protein TFF2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
11.9 kDa
20 µg/$1,107
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
13kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
TFF2 / SP Protein - SDS-PAGE under reducing conditions and visualized by Coomassie blue staining
Select
HEK 293 Cells
6His, N-terminus + Mouse IgG Fc, C-terminus
45-50 kDa
10 µg/$289; 50 µg/$360; 100 µg/$432
TFF2 / SP Protein - 12.5% SDS-PAGE of human TFF2 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
39.93 kDa
10 µg/$479; 25 µg/$670
TFF2 / SP Protein
Select
E. coli
6His, N-terminus
14.3 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
Select
Mammalian Cells
6His, C-terminus
Less than 0.1 ng/mL (Less than 1 EU/µg) (determined by LAL method).
10 µg/$269; 50 µg/$372; 500 µg/$1,245; 1 mg/$1,627
Select
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
12.7 kDa
10 µg/$269; 50 µg/$368
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
13.0 kDa
10 µg/$288; 50 µg/$436
Select
E. coli
None
11.9 kDa
20 µg/$349; 5 µg/$268
TFF2 / SP Protein
Select
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~12.3 kDa
20 µg/$291; 100 µg/$508; 1 mg/$2,851
TFF2 / SP Protein
Select
E. coli
None
Biologically active
12.0 kDa
5 µg/$282; 100 µg/$957; 500 µg/$1,747
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
12.0 kDa
5 µg/$268; 20 µg/$349
TFF2 / SP Protein - Recombinant Trefoil Factor 2 By SDS-PAGE
Select
E. coli
His
13.0 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
TFF2 / SP Protein - Recombinant Trefoil Factor 2 By SDS-PAGE
Select
E. coli
His
13.0 kDa
10 µg/$281; 50 µg/$440; 100 µg/$702; 200 µg/$877; 1 mg/$1,983; 500 µg/$1,523; 5 mg/$3,067; 2 mg/$2,170
TFF2 / SP Protein - Recombinant Trefoil Factor 2 By SDS-PAGE
Select
E. coli
His
13.0 kDa
10 µg/$268; 50 µg/$362; 100 µg/$577; 200 µg/$722; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934
TFF2 / SP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
14.28 kDa
20 µg/$150
TFF2 / SP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
14.28 kDa
100 µg/$494
Viewing 1-17 of 17 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).