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TFF1 / pS2

trefoil factor 1

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. TFF1, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. The TFF1 gene consists of 3 exons, with exon 2 encoding the trefoil domain. The TFF1, TFF2, and TFF3 genes are located within a 55 kb region, suggesting they evolved from a common ancestor by duplication.

Gene Name: trefoil factor 1
Synonyms: TFF1, BCEI, D21S21, HPS2, PNR-2, Polypeptide P1.A, Protein pS2, PS2, HP1.A, Trefoil factor 1
Target Sequences: NM_003225 NP_003216.1 P04155

Publications (2)

1
Gastric TFF1 Expression from Acute to ChronicHelicobacterInfection. Esposito R, Morello S, Vllahu M, Eletto D, Porta A, Tosco A. Frontiers in cellular and infection microbiology. 2017 October;7:434. (Human) [Full Text Article] [PubMed:29085807] [PMC:PMC5649190] Related Antibodies: LS-C155659.
2
C/EBPa Epigenetically Modulates TFF1 Expression via mC-6 Methylation in the Jejunum Inflammation Induced by a Porcine Coronavirus. Huan Qu, Qiufang Zong, Haifei Wang, Shenglong Wu, Demin Cai, Wenbin Bao. Frontiers in immunology. 2022 June;13:881289. [Full Text Article] [PubMed:35693767] [PMC:PMC9174463] Related Antibodies: LS-C312842.

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Products
ELISA Kits (18)
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Development Kit (1)
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TFF1 / pS2 (18)
Human (8)
Mouse (4)
Rat (2)
Dog (1)
Monkey (1)
Porcine (1)
Rabbit (1)
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12 x 8-Well Microstrips (1)
96-Well Microplate (2)
96-Well Strip Plate (14)
Antibody Pair and Standard (1)
No (18)
Cell Culture Supernatants (5)
Cell Lysates (2)
Plasma (12)
Serum (12)
Tissue Homogenates (4)
TFF1 / pS2 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$818
TFF1 / pS2 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$1,150
TFF1 / pS2 ELISA Kit
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Sandwich
96-Well Strip Plate
Porcine
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
TFF1 / pS2 ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
TFF1 / pS2 ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
5 - 320 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
TFF1 / pS2 ELISA Kit
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Development Kit
Antibody Pair and Standard
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
500 Wells/$1,254; 1000 Wells/$1,867
TFF1 / pS2 ELISA Kit
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Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
TFF1 / pS2 ELISA Kit
Select
Custom
96-Well Strip Plate
Dog
Colorimetric - 450nm (TMB)
1 Plate/$929
TFF1 / pS2 ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
TFF1 / pS2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$717
TFF1 / pS2 ELISA Kit
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Sandwich
96-Well Microplate
Human
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
TFF1 / pS2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
TFF1 / pS2 ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Human
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
TFF1 / pS2 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
2.5 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
TFF1 / pS2 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$1,150
TFF1 / pS2 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
78.13 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$856
TFF1 / pS2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$798
TFF1 / pS2 ELISA Kit
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Competitive EIA
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).