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TFDP2 / DP2
transcription factor Dp-2 (E2F dimerization partner 2)
Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1/DP complex appears to mediate both cell proliferation and apoptosis.
| Gene Name: | transcription factor Dp-2 (E2F dimerization partner 2) |
| Synonyms: | TFDP2, DP2, E2F dimerization partner 2, Dp-2, Transcription factor Dp-2 |
| Target Sequences: | U18422 NP_006277.1 Q14188 |
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