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TFB2M

transcription factor B2, mitochondrial

S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.

Gene Name: transcription factor B2, mitochondrial
Synonyms: TFB2M, H-mtTFB, H-mtTFB2, HTFB2M, MtTFB2, Hkp1, NS5ATP5
Target Sequences: NM_022366 NP_071761.1 Q9H5Q4

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Products
Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
TFB2M (6)
No (6)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (2)
TFB2M Protein - 12.5% SDS-PAGE of human TFB2M stained with Coomassie Blue
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Wheat Germ Extract
GST
71.7 kDa
2 µg/$439
TFB2M Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
TFB2M Protein - Purified recombinant protein TFB2M was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
45.2 kDa
20 µg/$1,107
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293T Cells
Myc-DDK (Flag)
45.2 kDa
20 µg/$150
TFB2M Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
45.2 kDa
100 µg/$494
TFB2M Protein
Select
E. coli
His
50 µg/$357; 250 µg/$692; 10 µg/$272; 20 µg/$317; 100 µg/$452; 500 µg/$1,147
Viewing 1-6 of 6 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).