TFAP2A / AP-2

transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)

Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region. Caution: AP-2B refers to both an alternatively spliced form of AP-2 and to the related transcription factor AP-2 beta.

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Products

ELISA Kits (2)

Type

Cell-Based (1)

DNA Binding (1)

Target

TFAP2A / AP-2 (2)

Reactivity

Human (2)

Mouse (2)

Rat (2)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (1)

Publications

No (2)

Sample Type

Adherent Cell Cultures (1)

Cell Lysates (1)

Nuclear Lysates (1)

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Mouse/Human/Rat TFAP2A / AP-2 (DNA-Binding ELISA) ELISA Kit - LS-F736

Type:

DNA Binding

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Nuclear Lysates

Price:

1 Plate/$694

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Mouse/Human/Rat TFAP2A / AP-2 (Cell-Based ELISA) ELISA Kit - LS-F1799

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$618

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