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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TET2

tet methylcytosine dioxygenase 2

Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in active DNA demethylation. Has a preference for 5-hydroxymethylcytosine in CpG motifs. Also mediates subsequent conversion of 5hmC into 5-formylcytosine (5fC), and conversion of 5fC to 5-carboxylcytosine (5caC). Conversion of 5mC into 5hmC, 5fC and 5caC probably constitutes the first step in cytosine demethylation. Methylation at the C5 position of cytosine bases is an epigenetic modification of the mammalian genome which plays an important role in transcriptional regulation. In addition to its role in DNA demethylation, also involved in the recruitment of the O-GlcNAc transferase OGT to CpG-rich transcription start sites of active genes, thereby promoting histone H2B GlcNAcylation by OGT.

Gene Name: tet methylcytosine dioxygenase 2
Synonyms: TET2, MDS, KIAA1546, Tet oncogene family member 2
Target Sequences: AB046766 BAB13372.1 Q6N021

Filtered by: None
Target
TET2 (27)
Reactivity
Human (26)
Mouse (9)
Rat (6)
Application
IHC (8)
IHC-P (5)
WB (24)
ELISA (14)
IF (1)
IP (1)
Peptide-ELISA (2)
Host
rabbit (25)
goat (2)
Isotype
IgG (20)
Clonality
polyclonal pc (27)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (21)
Epitope
aa528-554 (8)
aa100-150 (1)
aa1833-2002 (1)
aa254-267 (1)
aa761-775 (1)
Publications
No (27)
Showing 1-25 of 27 results

TET2 Antibody LS-C334211
Rabbit Polyclonal (IgG) to Human TET2
Mouse, Rat, Human
IHC-P, WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

TET2 Antibody (aa100-150) LS-C290887
Rabbit Polyclonal (IgG) to Human TET2
Human
IHC, IHC-P, IP, WB
Unconjugated
100µl 1mg/ml  $395.00
Detection of Human TET2 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-TET2 used at a dilution of 1:5000 (0.2 Detection: DAB.
Detection of Human TET2 by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa, 293T, and Jurkat cells. Antibodies: Affinity purified rabbit anti-TET2 antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

TET2 Antibody (aa1833-2002) LS-C377947
Rabbit Polyclonal (IgG) to Human TET2
Human
ELISA, IHC, IHC-P
Unconjugated
50µl 1.06mg/ml  $235.00; 100µl  $285.00
Immunohistochemistry of paraffin-embedded human breast cancer using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human ovarian cancer using antibody at 1:100 dilution.

TET2 Antibody LS-C336148
Rabbit Polyclonal (IgG) to Human TET2
Mouse, Human
ELISA, WB
Unconjugated
0.1mg 1mg/ml  $365.00
Western blot analysis of TET2 in 3T3 cell lysate with TET2 antibody at 1 ug/ml.

TET2 Antibody LS-C153760
Rabbit Polyclonal (IgG) to Human TET2
Human
ELISA, IF, IHC, WB
Unconjugated
0.1mg 1mg/ml  $365.00
Immunohistochemistry of TET2 in human colon carcinoma tissue with TET2 antibody at 2 µg/ml.
Immunofluorescence of TET2 in human colon carcinoma tissue with TET2 antibody at 20 µg/ml.

TET2 Antibody LS-C660969
Rabbit Polyclonal (IgG) to Human TET2
Human
ELISA, IHC, WB
Unconjugated
100µg  $435.00

TET2 Antibody LS-C802598
Rabbit Polyclonal (IgG) to Human TET2
Mouse, Human
ELISA, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunohistochemistry Image
Western blot Image

TET2 Antibody LS-C668553
Rabbit Polyclonal to Human TET2
Human
IHC, IHC-P, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $275.00
Immunohistochemistry - Paraffin Image
Western blot Image

TET2 Antibody LS-C341814
Rabbit Polyclonal to Human TET2
Human
IHC, WB
Unconjugated
100µl 1mg/ml  $385.00

TET2 Antibody LS-C771119
Rabbit Polyclonal (IgG) to Human TET2
Mouse, Rat, Human
IHC, WB
Unconjugated
60µl 1mg/ml  $235.00; 120µl 1mg/ml  $295.00; 200µl 1mg/ml  $395.00

TET2 Antibody (aa528-554) LS-C325670
Rabbit Polyclonal (IgG) to Human TET2
Human
ELISA, WB
Unconjugated
200µl  $590.00

TET2 Antibody (aa528-554, Biotin) LS-C224300
Rabbit Polyclonal (IgG) to Human TET2
Human
ELISA, WB
Biotin Conjugated
200µl  $740.00

TET2 Antibody (aa528-554, FITC) LS-C224304
Rabbit Polyclonal (IgG) to Human TET2
Human
ELISA, WB
FITC Conjugated
200µl  $740.00

TET2 Antibody (aa528-554, AP) LS-C224297
Rabbit Polyclonal (IgG) to Human TET2
Human
ELISA, WB
AP Conjugated
200µl  $740.00

TET2 Antibody (aa528-554, APC) LS-C224298
Rabbit Polyclonal (IgG) to Human TET2
Human
ELISA, WB
APC Conjugated
200µl  $740.00

TET2 Antibody (aa528-554, PE) LS-C224301
Rabbit Polyclonal (IgG) to Human TET2
Human
ELISA, WB
PE Conjugated
200µl  $740.00

TET2 Antibody (aa528-554, Azide-free, HRP) LS-C224302
Rabbit Polyclonal (IgG) to Human TET2
Human
ELISA, WB
HRP Conjugated, Azide-free
200µl  $740.00

TET2 Antibody LS-C744617
Rabbit Polyclonal to Human TET2
Human
ELISA, WB
Unconjugated
100µl 72.5mg/ml  $425.00
Western Blot of rabbit Anti-Tet2 Antibody. Lane 1: Whole Cell Extract. Lane 2: Cytosolic Extract. Lane 3: Nuclear Extract. Lane 4: Chromatin Fraction. Load: 35 µg per lane. Primary antibody: TET2 antibody at 1:5000 for 5 hours at room temperature. Secondary antibody: HRP rabbit secondary antibody at 1:10,000 for 45 min at RT. Block: 5% BLOTTO overnight at 4°C. Predicted/Observed size: ~230 and ~150kDa. Other band(s): nonspecific.

TET2 Antibody LS-C744616
Rabbit Polyclonal to Human TET2
Human
ELISA, WB
Unconjugated
25µl 72.5mg/ml  $235.00
Western Blot of rabbit Anti-Tet2 Antibody. Lane 1: Whole Cell Extract. Lane 2: Cytosolic Extract. Lane 3: Nuclear Extract. Lane 4: Chromatin Fraction. Load: 35 µg per lane. Primary antibody: TET2 antibody at 1:5000 for 5 hours at room temperature. Secondary antibody: HRP rabbit secondary antibody at 1:10,000 for 45 min at RT. Block: 5% BLOTTO overnight at 4°C. Predicted/Observed size: ~230 and ~150kDa. Other band(s): nonspecific.

TET2 Antibody (aa761-775) LS-C112875
Goat Polyclonal to Human TET2
Human
IHC-P, Peptide-ELISA
Unconjugated
100µg 0.5mg/ml  $405.00
Goat Anti-TET2  Antibody (4µg/ml) staining of paraffin embedded Human Spleen. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.

TET2 Antibody LS-C409077
Rabbit Polyclonal (IgG) to Human TET2
Human
WB
Unconjugated
50µl  $315.00; 100µl  $425.00; 200µl  $650.00

TET2 Antibody LS-C771118
Rabbit Polyclonal (IgG) to Human TET2
Mouse, Rat, Human
WB
Unconjugated
60µl 1mg/ml  $235.00; 120µl 1mg/ml  $295.00; 200µl 1mg/ml  $395.00

TET2 Antibody LS-C771117
Rabbit Polyclonal (IgG) to Human TET2
Mouse, Rat, Human
WB
Unconjugated
60µl 1mg/ml  $235.00; 120µl 1mg/ml  $295.00; 200µl 1mg/ml  $395.00

TET2 Antibody (aa254-267) LS-C154860
Goat Polyclonal to Mouse TET2
Mouse, Rat
Peptide-ELISA
Unconjugated
100µg 0.5mg/ml  $335.00

TET2 Antibody (aa528-554) LS-C157167
Rabbit Polyclonal to Human TET2
Human
WB
Unconjugated
400µl  $325.00
TET2 Antibody western blot of A549 cell line lysates (35 ug/lane). The TET2 antibody detected the TET2 protein (arrow).
Showing 1-25 of 27 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).