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Testilin / EHD1
EH-domain containing 1
Testilin / EHD1 belongs to a highly conserved gene family encoding EPS15 homology (EH) domain-containing proteins. The protein-binding EH domain was first noted in EPS15, a substrate for the epidermal growth factor receptor. The EH domain has been shown to be an important motif in proteins involved in protein-protein interactions and in intracellular sorting. The protein encoded by this gene is thought to play a role in the endocytosis of IGF1 receptors. Alternatively spliced transcript variants have been found for this gene.
| Gene Name: | EH-domain containing 1 |
| Synonyms: | EHD1, EH domain-containing protein 1, EH-domain containing 1, HPAST1, PAST, PAST homolog 1, PAST1, H-PAST, Testilin |
| Target Sequences: | NM_006795 NP_006786.2 Q9H4M9 |
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