TDP1

tyrosyl-DNA phosphodiesterase 1

DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3'-phosphodiester bond, giving rise to DNA with a free 3' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase I active site tyrosine residue. Hydrolyzes 3'-phosphoglycolates on protruding 3' ends on DNA double-strand breaks due to DNA damage by radiation and free radicals. Acts on blunt-ended double-strand DNA breaks and on single-stranded DNA. Has low 3'exonuclease activity and can remove a single nucleoside from the 3'end of DNA and RNA molecules with 3'hydroxyl groups. Has no exonuclease activity towards DNA or RNA with a 3'phosphate.

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Products

Antibodies (36)

Proteins (11)

ELISA Kits (1)

Type

Over-Expression Lysate (4)

Primary (36)

Recombinant (7)

Sandwich (1)

Target

TDP1 (48)

Reactivity

Human (27)

Mouse (25)

Rat (5)

Bovine (3)

Chimpanzee (6)

Gibbon (6)

Guinea pig (3)

Hamster (3)

Horse (6)

Monkey (6)

Orangutan (3)

Xenopus (3)

Zebrafish (3)

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Application

IHC (6)

IHC-P (3)

WB (32)

ELISA (11)

IF (2)

IP (3)

Peptide-ELISA (1)

Host

rabbit (32)

mouse (4)

Product Group

IHCPlus (1)

Isotype

IgG (15)

IgG1 (2)

IgG2b,k (2)

Clonality

monoclonal mc (4)

polyclonal pc (32)

Clone

AT1F2 (1)

OTI4H1 (2)

Format

96-Well Strip Plate (1)

APC (1)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (4)

Carrier-free (1)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (2)

Unconjugated (18)

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Epitope

aa212-239 (7)

aa350-399 (4)

aa428-477 (4)

aa1-260 (2)

aa1-50 (2)

aa1-298 (1)

aa75-125 (1)

Publications

No (48)

Sample Type

Cell Culture Supernatants (1)

Cell Lysates (1)

Plasma (1)

Serum (1)

Tissue Homogenates (1)

Tag

GST (1)

GST, N-terminus (1)

His (1)

His-GST, N-terminus (1)

Myc-DDK (Flag) (6)

Species

Human (7)

Mouse (1)

Rat (1)

Source

293T Cells (2)

E. coli (3)

HEK 293 Cells (4)

Wheat Germ Extract (2)

Purification

Purified (4)

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IHC-plus™ TDP1 Antibody (clone AT1F2) LS-B3586

(4.0) Rating

Antibody:

TDP1 Mouse anti-Human Monoclonal (AT1F2) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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TDP1 Antibody (aa1-260) LS-C376759

Antibody:

TDP1 Rabbit anti-Human Polyclonal (aa1-260) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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TDP1 Antibody LS-C409528

Antibody:

TDP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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TDP1 Antibody (aa1-260) LS-C376761

Antibody:

TDP1 Rabbit anti-Human Polyclonal (aa1-260) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

TDP1 Antibody (aa1-50) LS-C288407

Antibody:

TDP1 Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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TDP1 Antibody LS-C660951

Antibody:

TDP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$341

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TDP1 Antibody (aa1-298) LS-C132776

Antibody:

TDP1 Mouse anti-Human Monoclonal (aa1-298) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$586

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TDP1 Antibody (aa212-239) LS-C325650

Antibody:

TDP1 Rabbit anti-Human Polyclonal (aa212-239) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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TDP1 Antibody (aa212-239, Biotin) LS-C241677

Antibody:

TDP1 Rabbit anti-Human Polyclonal (aa212-239) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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TDP1 Antibody (aa212-239, FITC) LS-C241678

Antibody:

TDP1 Rabbit anti-Human Polyclonal (aa212-239) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

TDP1 Antibody (aa212-239, APC) LS-C241676

Antibody:

TDP1 Rabbit anti-Human Polyclonal (aa212-239) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

TDP1 Antibody (aa212-239, PE) LS-C241681

Antibody:

TDP1 Rabbit anti-Human Polyclonal (aa212-239) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

TDP1 Antibody (aa212-239, Azide-free, HRP) LS-C247041

Antibody:

TDP1 Rabbit anti-Human Polyclonal (aa212-239) (Azide-free) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

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TDP1 Antibody LS-C809060

Antibody:

TDP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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TDP1 Antibody LS-C834498

Antibody:

TDP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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TDP1 Antibody (aa350-399) LS-C135430

Antibody:

TDP1 Rabbit anti-Mouse Polyclonal (aa350-399) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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TDP1 Antibody (aa428-477) LS-C201691

Antibody:

TDP1 Rabbit anti-Mouse Polyclonal (aa428-477) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

TDP1 Antibody (aa1-50) LS-C286561

Antibody:

TDP1 Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Human

Applications:

IHC

Format:

Unconjugated

Price:

2.5 µg/$295; 100 µl/$532

Select

TDP1 Antibody LS-C663261

Antibody:

TDP1 Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261

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TDP1 Antibody (HRP) LS-C711916

Antibody:

TDP1 Rabbit anti-Mouse Polyclonal (HRP) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639

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TDP1 Antibody (Biotin) LS-C687453

Antibody:

TDP1 Rabbit anti-Mouse Polyclonal (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387

Select

TDP1 Antibody (FITC) LS-C694280

Antibody:

TDP1 Rabbit anti-Mouse Polyclonal (FITC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

TDP1 Antibody (clone OTI4H1) LS-C337530

Antibody:

TDP1 Mouse anti-Human Monoclonal (OTI4H1) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

Select

TDP1 Antibody (clone OTI4H1, Carrier-free) LS-C786574

Antibody:

TDP1 Mouse anti-Human Monoclonal (Carrier-free) (OTI4H1) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

TDP1 Antibody (aa212-239) LS-C157164

Antibody:

TDP1 Rabbit anti-Human Polyclonal (aa212-239) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Viewing 1-25 of 48 product results

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