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Unfortunately, the antibody (ID:187717) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



TDP-43 / TARDBP

TAR DNA binding protein

DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cell division. Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat. Stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3' UTR.

Gene Name: TAR DNA binding protein
Synonyms: TARDBP, ALS10, TAR DNA-binding protein-43, TDP-43, TAR DNA binding protein, TAR DNA-binding protein 43, TDP43
Target Sequences: NM_007375 NP_031401.1 Q13148

Publications (5)

1
Evidence of multisystem disorder in whole-brain map of pathological TDP-43 in amyotrophic lateral sclerosis. Geser F, Brandmeir NJ, Kwong LK, Martinez-Lage M, Elman L, McCluskey L, Xie SX, Lee VM, Trojanowski JQ. Archives of neurology. 2008 65:636-41. [PubMed:18474740]
2
TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration. Wegorzewska I, Bell S, Cairns NJ, Miller TM, Baloh RH. Proceedings of the National Academy of Sciences of the United States of America. 2009 106:18809-14. [PubMed:19833869] [PMC:PMC2762420]
3
Downregulation of VAPB expression in motor neurons derived from induced pluripotent stem cells of ALS8 patients. Mitne-Neto M, Machado-Costa M, Marchetto MC, Bengtson MH, Joazeiro CA, Tsuda H, Bellen HJ, Silva HC, Oliveira AS, Lazar M, Muotri AR, Zatz M. Human molecular genetics. 2011 20:3642-52. [PubMed:21685205] [PMC:PMC3159551]
4
TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes. Kawahara Y, Mieda-Sato A. Proceedings of the National Academy of Sciences of the United States of America. 2012 109:3347-52. [PubMed:22323604] [PMC:PMC3295278]
5
Sialylation and muscle performance: sialic acid is a marker of muscle ageing. Hanisch F, Weidemann W, Gro[Character df]mann M, Joshi PR, Holzhausen HJ, Stoltenburg G, Weis J, Zierz S, Horstkorte R. PloS one. 2013 8:e80520. [Full Text Article] [PubMed:24349002] [PMC:PMC3859654] Related Antibodies: LS-C30991.
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Filtered By: None
Target
tdp-43-tardbp (65)
Reactivity
Human (61)
Mouse (44)
Rat (31)
Bat (17)
Bovine (19)
Chicken (19)
Chimpanzee (12)
Dog (18)
Gibbon (12)
Guinea pig (16)
Hamster (1)
Horse (18)
Monkey (17)
Orangutan (9)
Pig (14)
Primate (5)
Rabbit (13)
Xenopus (5)
Zebrafish (9)
Application
IHC (24)
IHC-Fr (4)
IHC-P (25)
WB (65)
ELISA (25)
IF (12)
IP (3)
RNAi (1)
RnaIP (1)
Host
rabbit (54)
mouse (3)
goat (1)
rat (7)
Isotype
IgG (41)
IgG1 (1)
IgG1,k (2)
IgG2a,k (7)
Clonality
monoclonal mc (10)
polyclonal pc (55)
Clone
2E2-D3 (1)
3H8 (1)
K1B8 (1)
Format
AP Conjugated (3)
APC Conjugated (2)
Biotin Conjugated (10)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
FITC Conjugated (9)
HRP Conjugated (7)
PE Conjugated (3)
Unconjugated (28)
Epitope
C-Terminus (6)
aa1-30 (6)
aa104-262 (6)
N-Terminus (5)
aa252-301 (4)
aa337-386 (4)
aa72-121 (4)
aa1-260 (2)
aa250-300 (2)
Internal (1)
aa140-153 (1)
aa150-200 (1)
aa350-414 (1)
Publications
No (64)
Yes (1)
Showing 1-25 out of 65 results
Anti-TDP-43 / TARDBP Antibody (clone 2E2-D3) IHC-plus™ LS-B4521

Mouse Monoclonal [clone 2E2-D3] (IgG1,k) to Human TDP-43 / TARDBP
Human
ELISA IF IHC-P RNAi WB
Unconjugated
Anti-TDP-43 / TARDBP Antibody (aa1-260, clone K1B8) IHC-plus™ LS-B2957

Mouse Monoclonal [clone K1B8] (IgG1,k) to Human TDP-43 / TARDBP
Human
ELISA IHC-P WB
Unconjugated
Anti-TDP-43 / TARDBP Antibody (Internal) IHC-plus™ LS-B2223

Rabbit Polyclonal (IgG) to Human TDP-43 / TARDBP
Mouse, Rat, Human
IHC-P WB
Unconjugated
Anti-TDP-43 / TARDBP Antibody (C-Terminus) LS-C144920

Rabbit Polyclonal to Mouse TDP-43 / TARDBP
Mouse
IHC WB
Unconjugated
Anti-TDP-43 / TARDBP Antibody (aa337-386) LS-C30991

Rabbit Polyclonal (IgG) to Human TDP-43 / TARDBP
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Bat, Human, Monkey
IHC-Fr WB
Unconjugated
Anti-TDP-43 / TARDBP Antibody (clone 3H8) IHC-plus™ LS-B12387

Mouse Monoclonal [clone 3H8] (IgG1) to Human TDP-43 / TARDBP
Mouse, Bovine, Rat, Pig, Human
IF IHC-P WB
Unconjugated
Anti-TDP-43 / TARDBP Antibody (aa350-414) IHC-plus™ LS-B321

Rabbit Polyclonal to Human TDP-43 / TARDBP
Xenopus, Chicken, Zebrafish, Mouse, Primate, Human
IHC-P WB
Unconjugated
Anti-TDP-43 / TARDBP Antibody (C-Terminus, Biotin) LS-C141483

Rabbit Polyclonal to Human TDP-43 / TARDBP
Xenopus, Chicken, Zebrafish, Mouse, Primate, Human
IHC IHC-P WB
Biotin Conjugated
Anti-TDP-43 / TARDBP Antibody (C-Terminus, DY650) LS-C141484

Rabbit Polyclonal to Human TDP-43 / TARDBP
Xenopus, Chicken, Zebrafish, Mouse, Primate, Human
IHC IHC-P WB
DY650 Conjugated
Anti-TDP-43 / TARDBP Antibody (C-Terminus, DY488) LS-C141485

Rabbit Polyclonal to Human TDP-43 / TARDBP
Xenopus, Chicken, Zebrafish, Mouse, Primate, Human
IHC IHC-P WB
DY488 Conjugated
Anti-TDP-43 / TARDBP Antibody (aa252-301) IHC-plus™ LS-B6796

Rabbit Polyclonal (IgG) to Human TDP-43 / TARDBP
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Pig, Horse, Bat, Human, Monkey
IHC-P WB
Unconjugated
Anti-TDP-43 / TARDBP Antibody LS-C124633

Rat Monoclonal (IgG2a,k) to Human TDP-43 / TARDBP
Human
ELISA IHC WB
Unconjugated
Anti-TDP-43 / TARDBP Antibody (aa1-30) IHC-plus™ LS-B10176

Rabbit Polyclonal to Human TDP-43 / TARDBP
Human
IF IHC-P WB
Unconjugated
Anti-TDP-43 / TARDBP Antibody (C-Terminus) IHC-plus™ LS-B4917

Rabbit Polyclonal to Human TDP-43 / TARDBP
Human
IHC-P WB
Unconjugated
Anti-TDP-43 / TARDBP Antibody (N-Terminus) LS-C30990

Rabbit Polyclonal (IgG) to Human TDP-43 / TARDBP
Chicken, Bovine, Rat, Pig, Horse, Bat, Mouse, Dog, Guinea pig, Human, Monkey
IHC-P WB
Unconjugated
Anti-TDP-43 / TARDBP Antibody LS-C331331

Rabbit Polyclonal (IgG) to Human TDP-43 / TARDBP
Mouse, Rat, Human
IF IHC IP RnaIP WB
Unconjugated
Anti-TDP-43 / TARDBP Antibody (aa1-30) LS-C325576

Rabbit Polyclonal (IgG) to Human TDP-43 / TARDBP
Mouse, Human
IF IHC WB
Unconjugated
Anti-TDP-43 / TARDBP Antibody (aa1-30, FITC) LS-C227109

Rabbit Polyclonal (IgG) to Human TDP-43 / TARDBP
Human
ELISA IF IHC WB
FITC Conjugated
Anti-TDP-43 / TARDBP Antibody (aa1-30, AP) LS-C224246

Rabbit Polyclonal (IgG) to Human TDP-43 / TARDBP
Human
ELISA IF IHC WB
AP Conjugated
Anti-TDP-43 / TARDBP Antibody (aa1-30, APC) LS-C224247

Rabbit Polyclonal (IgG) to Human TDP-43 / TARDBP
Human
ELISA IF IHC WB
APC Conjugated
Anti-TDP-43 / TARDBP Antibody (aa1-30, PE) LS-C227113

Rabbit Polyclonal (IgG) to Human TDP-43 / TARDBP
Human
ELISA IF IHC WB
PE Conjugated
Anti-TDP-43 / TARDBP Antibody (aa150-200) LS-C289923

Rabbit Polyclonal (IgG) to Human TDP-43 / TARDBP
Mouse, Human
IF IHC-P IP WB
Unconjugated
Anti-TDP-43 / TARDBP Antibody (aa250-300) LS-C289924

Rabbit Polyclonal (IgG) to Human TDP-43 / TARDBP
Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Pig, Horse, Human
IF IHC-P IP WB
Unconjugated
Anti-TDP-43 / TARDBP Antibody LS-C496677

Rabbit Polyclonal (IgG) to Human TDP-43 / TARDBP
Mouse, Human
IF IHC WB
Unconjugated
Anti-TDP-43 / TARDBP Antibody LS-C414791

Rabbit Polyclonal to Human TDP-43 / TARDBP
Mouse, Rat, Human
ELISA IHC WB
Unconjugated

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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