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TCF3 / E2A

transcription factor 3

TCF3 / E2A is a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.

Gene Name: transcription factor 3
Synonyms: TCF3, BHLHb21, E2A, E47, Helix-loop-helix protein HE47, Kappa-E2-binding factor, TCF-3, Transcription factor 3, Transcription factor E2-alpha, Transcription factor ITF-1, VDR interacting repressor, ITF1, VDIR
Target Sequences: M31523 AAA61146.1 P15923

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Products
Proteins (8)
Over-Expression Lysate (4)
Recombinant (4)
TCF3 / E2A (8)
No (8)
GST, N-terminus (1)
His, N-Terminal (1)
Myc-DDK (Flag) (6)
Human (6)
293T Cells (2)
E. coli (1)
HEK 293 Cells (4)
Wheat Germ Extract (1)
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HEK 293 Cells
Myc-DDK (Flag)
67.1 kDa
100 µg/$494
TCF3 / E2A Protein
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E. coli
His, N-Terminal
67.4 kDa
50 µg/$419
TCF3 / E2A Protein - Purified recombinant protein TCF3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
67.4 kDa
20 µg/$1,107
TCF3 / E2A Protein - Purified recombinant protein TCF3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
67.1 kDa
20 µg/$1,107
TCF3 / E2A Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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293T Cells
Myc-DDK (Flag)
67.1 kDa
20 µg/$150
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293T Cells
Myc-DDK (Flag)
67.4 kDa
20 µg/$215
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HEK 293 Cells
Myc-DDK (Flag)
67.4 kDa
100 µg/$710
Viewing 1-8 of 8 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).