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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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We could not find product '(ID:65740)'. Here are some alternate products to this target that might be of interest to you.
TCF3 / E2A
transcription factor 3
TCF3 / E2A is a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.
| Gene Name: | transcription factor 3 |
| Synonyms: | TCF3, BHLHb21, E2A, E47, Helix-loop-helix protein HE47, Kappa-E2-binding factor, TCF-3, Transcription factor 3, Transcription factor E2-alpha, Transcription factor ITF-1, VDR interacting repressor, ITF1, VDIR |
| Target Sequences: | M31523 AAA61146.1 P15923 |
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