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TCEB3 / Elongin A

transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)

TCEB3 / Elongin A is the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.

Gene Name: transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
Synonyms: TCEB3, EloA, Elongin 110 kDa subunit, SIII, TCEB3A, Elongin A, Elongin-A, SIII p110
Target Sequences: NM_003198 NP_003189.2 Q14241

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Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
TCEB3 / Elongin A (6)
No (6)
GST (1)
GST, N-terminus (1)
His-T7 (2)
Myc-DDK (Flag) (2)
Human (3)
Mouse (1)
Rat (1)
293T Cells (1)
E. coli (2)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (1)
TCEB3 / Elongin A Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
TCEB3 / Elongin A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
87 kDa
20 µg/$150
TCEB3 / Elongin A Protein - Recombinant Elongin A By SDS-PAGE
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E. coli
His-T7
34.6 kDa
50 µg/$432; 10 µg/$279; 200 µg/$862; 100 µg/$690; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
TCEB3 / Elongin A Protein - Recombinant Elongin A By SDS-PAGE
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E. coli
His-T7
19.9 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
TCEB3 / Elongin A Protein - 12.5% SDS-PAGE of human TCEB3 stained with Coomassie Blue
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Wheat Germ Extract
GST
113.6 kDa
2 µg/$439
TCEB3 / Elongin A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
87 kDa
100 µg/$494
Viewing 1-6 of 6 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).