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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TCEB1 / Elongin C

transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)

SIII / TCEB1 is the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified.

Gene Name: transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
Synonyms: TCEB1, Elongin 15 kDa subunit, EloC, SIII, SIII p15, Elongin-C
Target Sequences: NM_005648 NP_005639.1 Q15369

Publications (3)

1
COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase. Maine GN, Mao X, Komarck CM, Burstein E. The EMBO journal. 2007 26:436-47. [PubMed:17183367] [PMC:PMC1783443]
2
GCN5 is a required cofactor for a ubiquitin ligase that targets NF-kappaB/RelA. Mao X, Gluck N, Li D, Maine GN, Li H, Zaidi IW, Repaka A, Mayo MW, Burstein E. Genes & development. 2009 23:849-61. [PubMed:19339690] [PMC:PMC2666342]
3
COMMD1 (copper metabolism MURR1 domain-containing protein 1) regulates Cullin RING ligases by preventing CAND1 (Cullin-associated Nedd8-dissociated protein 1) binding. Mao X, Gluck N, Chen B, Starokadomskyy P, Li H, Maine GN, Burstein E. The Journal of biological chemistry. 2011 286:32355-65. [PubMed:21778237] [PMC:PMC3173175]

Filtered By: None
Target
TCEB1 / Elongin C (37)
Reactivity
Human (37)
Mouse (11)
Rat (11)
Bovine (8)
Chicken (8)
Chimpanzee (6)
Dog (8)
Drosophila (4)
Gibbon (6)
Guinea pig (8)
Hamster (8)
Horse (8)
Monkey (8)
Pig (8)
Rabbit (4)
Xenopus (8)
Zebrafish (8)
Application
IHC (26)
IHC-P (6)
WB (36)
ELISA (13)
Host
rabbit (34)
chicken (3)
Isotype
IgG (24)
IgY (1)
Clonality
polyclonal pc (37)
Format
AP Conjugated (1)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (5)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (2)
Unconjugated (15)
Epitope
aa69-98 (8)
aa34-83 (4)
aa53-102 (4)
Publications
No (37)
Showing 1-25 of 37 results

TCEB1 / Elongin C Antibody IHC-plus™ LS-B12995
Rabbit Polyclonal (IgG) to Human TCEB1 / Elongin C
Human
ELISA IHC IHC-P WB
Unconjugated
50µg  $425.00
Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TCEB1 / Elongin C Antibody (HRP) LS-C318440
Rabbit Polyclonal (IgG) to Human TCEB1 / Elongin C
Human
ELISA IHC IHC-P WB
HRP Conjugated
50µg  $285.00; 100µg  $385.00
Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TCEB1 / Elongin C Antibody (Biotin) LS-C318439
Rabbit Polyclonal (IgG) to Human TCEB1 / Elongin C
Human
ELISA IHC IHC-P WB
Biotin Conjugated
50µg  $285.00; 100µg  $385.00
Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TCEB1 / Elongin C Antibody (FITC) LS-C318438
Rabbit Polyclonal (IgG) to Human TCEB1 / Elongin C
Human
ELISA IHC IHC-P WB
FITC Conjugated
50µg  $285.00; 100µg  $385.00
Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.

TCEB1 / Elongin C Antibody LS-C84030
Chicken Polyclonal to Human TCEB1 / Elongin C
Human
IHC WB
Unconjugated
1000µg 17mg/ml  $415.00

TCEB1 / Elongin C Antibody (aa69-98) LS-C325632
Rabbit Polyclonal (IgG) to Human TCEB1 / Elongin C
Human
ELISA IHC WB
Unconjugated
200µl  $530.00

TCEB1 / Elongin C Antibody (aa69-98, Biotin) LS-C207733
Rabbit Polyclonal (IgG) to Human TCEB1 / Elongin C
Human
ELISA IHC WB
Biotin Conjugated
200µl  $680.00

TCEB1 / Elongin C Antibody (aa69-98, FITC) LS-C207735
Rabbit Polyclonal (IgG) to Human TCEB1 / Elongin C
Human
ELISA IHC WB
FITC Conjugated
200µl  $680.00

TCEB1 / Elongin C Antibody (aa69-98, APC) LS-C207734
Rabbit Polyclonal (IgG) to Human TCEB1 / Elongin C
Human
ELISA IHC WB
APC Conjugated
200µl  $680.00

TCEB1 / Elongin C Antibody (aa69-98, Azide-free, HRP) LS-C207736
Rabbit Polyclonal (IgG) to Human TCEB1 / Elongin C
Human
ELISA IHC WB
HRP Conjugated, Azide-free
200µl  $680.00

TCEB1 / Elongin C Antibody (aa69-98, PE) LS-C207737
Rabbit Polyclonal (IgG) to Human TCEB1 / Elongin C
Human
ELISA IHC WB
PE Conjugated
200µl  $680.00

TCEB1 / Elongin C Antibody (aa69-98, AP) LS-C207732
Rabbit Polyclonal (IgG) to Human TCEB1 / Elongin C
Human
ELISA IHC WB
AP Conjugated
200µl  $680.00

TCEB1 / Elongin C Antibody LS-C660931
Rabbit Polyclonal (IgG) to Human TCEB1 / Elongin C
Human
ELISA IHC WB
Unconjugated
100µg  $435.00

TCEB1 / Elongin C Antibody LS-C497929
Rabbit Polyclonal (IgG) to Human TCEB1 / Elongin C
Mouse, Rat, Human
IHC WB
Unconjugated
50µl  $235.00; 100µl  $295.00; 200µl  $385.00
Immunohistochemistry of paraffin-embedded mouse liver tissue.
Immunohistochemistry of paraffin-embedded rat kidney tissue.
Immunohistochemistry of paraffin-embedded mouse liver tissue.
Immunohistochemistry of paraffin-embedded rat kidney tissue.

TCEB1 / Elongin C Antibody (aa69-98) LS-C161764
Rabbit Polyclonal to Human TCEB1 / Elongin C
Human
IHC IHC-P WB
Unconjugated
400µl  $305.00
TCEB1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human prostate carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
TCEB1 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The TCEB1 antibody detected the TCEB1 protein (arrow).
TCEB1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human prostate carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
TCEB1 Antibody western blot of Jurkat cell line lysates (35 ug/lane). The TCEB1 antibody detected the TCEB1 protein (arrow).

TCEB1 / Elongin C Antibody LS-C668211
Rabbit Polyclonal to Human TCEB1 / Elongin C
Human
IHC IHC-P WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $275.00
Immunohistochemistry - Paraffin Image
Western blot Image
Immunohistochemistry - Paraffin Image
Western blot Image

TCEB1 / Elongin C Antibody LS-C409075
Rabbit Polyclonal (IgG) to Human TCEB1 / Elongin C
Human
IHC WB
Unconjugated
100µl  $295.00; 200µl  $385.00

TCEB1 / Elongin C Antibody LS-C412311
Rabbit Polyclonal to Human TCEB1 / Elongin C
Mouse, Rat, Human
IHC WB
Unconjugated
100µl  $385.00

TCEB1 / Elongin C Antibody LS-C663471
Rabbit Polyclonal to Human TCEB1 / Elongin C
Human
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $530.00; 10ml 0.5mg/ml  $2,100.00
DAB staining on fromalin fixed paraffin- embedded rectum tissue
Western Blot; Sample: Recombinant protein.
DAB staining on fromalin fixed paraffin- embedded rectum tissue
Western Blot; Sample: Recombinant protein.

TCEB1 / Elongin C Antibody (HRP) LS-C712884
Rabbit Polyclonal to Human TCEB1 / Elongin C
Human
IHC WB
HRP Conjugated
20µl  $215.00; 100µl  $285.00; 200µl  $345.00; 1ml  $680.00; 10ml  $2,730.00
DAB staining on fromalin fixed paraffin- embedded rectum tissue
Western Blot; Sample: Recombinant protein.
DAB staining on fromalin fixed paraffin- embedded rectum tissue
Western Blot; Sample: Recombinant protein.

TCEB1 / Elongin C Antibody (Biotin) LS-C688208
Rabbit Polyclonal to Human TCEB1 / Elongin C
Human
IHC WB
Biotin Conjugated
20µl  $205.00; 100µl  $265.00; 200µl  $315.00; 1ml  $575.00; 10ml  $2,310.00
DAB staining on fromalin fixed paraffin- embedded rectum tissue
Western Blot; Sample: Recombinant protein.
DAB staining on fromalin fixed paraffin- embedded rectum tissue
Western Blot; Sample: Recombinant protein.

TCEB1 / Elongin C Antibody (FITC) LS-C695131
Rabbit Polyclonal to Human TCEB1 / Elongin C
Human
IHC WB
FITC Conjugated
20µl  $215.00; 100µl  $275.00; 200µl  $325.00; 1ml  $635.00; 10ml  $2,520.00
DAB staining on fromalin fixed paraffin- embedded rectum tissue
Western Blot; Sample: Recombinant protein.
DAB staining on fromalin fixed paraffin- embedded rectum tissue
Western Blot; Sample: Recombinant protein.

TCEB1 / Elongin C Antibody (Cy3) LS-C703862
Rabbit Polyclonal to Human TCEB1 / Elongin C
Human
IHC WB
Cy3 Conjugated
20µl  $245.00; 100µl  $355.00; 200µl  $445.00; 1ml  $1,050.00; 10ml  $4,200.00
DAB staining on fromalin fixed paraffin- embedded rectum tissue
Western Blot; Sample: Recombinant protein.
DAB staining on fromalin fixed paraffin- embedded rectum tissue
Western Blot; Sample: Recombinant protein.

TCEB1 / Elongin C Antibody (PE) LS-C726946
Rabbit Polyclonal to Human TCEB1 / Elongin C
Human
IHC WB
PE Conjugated
20µl  $215.00; 100µl  $275.00; 200µl  $325.00; 1ml  $635.00; 10ml  $2,520.00
DAB staining on fromalin fixed paraffin- embedded rectum tissue
Western Blot; Sample: Recombinant protein.
DAB staining on fromalin fixed paraffin- embedded rectum tissue
Western Blot; Sample: Recombinant protein.

TCEB1 / Elongin C Antibody (APC) LS-C741253
Rabbit Polyclonal to Human TCEB1 / Elongin C
Human
IHC WB
APC Conjugated
20µl  $225.00; 100µl  $305.00; 200µl  $375.00; 1ml  $785.00
DAB staining on fromalin fixed paraffin- embedded rectum tissue
Western Blot; Sample: Recombinant protein.
DAB staining on fromalin fixed paraffin- embedded rectum tissue
Western Blot; Sample: Recombinant protein.
Showing 1-25 of 37 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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