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TBRG1

transforming growth factor beta regulator 1

Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability.

Gene Name:	transforming growth factor beta regulator 1
Synonyms:	TBRG1, NIAM, TB-5
Target Sequences:	NM_032811 NP_116200.2 Q3YBR2

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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