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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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TBPL1 / TRF2
TBP-like 1
TBPL1 / TRF2 is a member of the TATA box-binding protein family. TATA box-binding proteins play a critical role in transcription by RNA polymerase II as components of the transcription factor IID (TFIID) complex. The encoded protein does not bind to the TATA box and initiates transcription from TATA-less promoters. This gene plays a critical role in spermatogenesis, and single nucleotide polymorphisms in this gene may be associated with male infertility. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3.
| Gene Name: | TBP-like 1 |
| Synonyms: | TBPL1, 21-kDA TBP-like protein, 21 kDa TBP-like protein, MGC:8389, TBP-related protein, TLP21, MGC:9620, TRF2, STUD, TBP-like 1, TBP-related factor 2, TLF, TBP-like factor, TBP-like protein 1, TLP |
| Target Sequences: | NM_004865 NP_004856.1 P62380 |
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