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Acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion.
Gene Name: | TBC1 Domain Family, Member 2 |
Synonyms: | TBC1D2, Armus, PARIS-1, PARIS1, TBC1 domain family member 2A, PP8997, TBC1 domain family, member 2, TBC1 domain family, member 2A, TBC1D2A |
Target Sequences: | NM_018421 NP_060891.3 Q9BYX2 |
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