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TBC1D17

TBC1 Domain Family, Member 17

Probable GTPase-activating protein for Rab8; its transient association with Rab8 is mediated by OPTN. Inhibits Rab8-mediated endocytic trafficking, such as of transferrin receptor (TfR) and reduces Rab8 recruitnment to tubules emanating from the endocytic recycling compartment (ERC). Involved in regulation of autophagy. Mediates inhibition of autophagy caused by the OPTN variant GLC1E LYS-50; the function requires its catalytic activity, however, the involved Rab is not known.

Gene Name: TBC1 Domain Family, Member 17
Synonyms: TBC1D17, TBC1 domain family member 17, TBC1 domain family, member 17
Target Sequences: NM_024682

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Proteins (2)
Over-Expression Lysate (2)
TBC1D17 (2)
No (2)
Myc-DDK (Flag) (2)
Human (1)
293T Cells (1)
HEK 293 Cells (1)
TBC1D17 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
69.4 kDa
20 µg/$150
TBC1D17 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
69.4 kDa
100 µg/$494
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).