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Small G proteins of the RAB family (see MIM 179508) function in intracellular vesicle trafficking by switching from the GTP-bound state to the GDP-bound state with the assistance of guanine nucleotide exchange factors (GEFs; see MIM 609700) and GTPase-activating proteins (GAPs). TBC1D10B functions as a GAP for several proteins of the Rab family (Ishibashi et al., 2009 [PubMed 19077034]).
Gene Name: | TBC1 domain family, member 10B |
Synonyms: | TBC1D10B, EPI64B, FP2461, TBC1 domain family member 10B, Rab27A-GAP-beta, DKFZP434P1750, Rab27A-GAPbeta, TBC1 domain family, member 10B |
Target Sequences: | NM_015527 NP_056342.3 Q4KMP7 |
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