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TAS2R38

taste receptor, type 2, member 38

TAS2R38 is a seven-transmembrane G protein-coupled receptor that controls the ability to taste glucosinolates, a family of bitter-tasting compounds found in plants of the Brassica sp. Synthetic compounds phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) have been identified as ligands for this receptor and have been used to test the genetic diversity of this gene. Although several allelic forms of this gene have been identified worldwide, there are two predominant common forms (taster and non-taster) found outside of Africa. These alleles differ at three nucleotide positions resulting in amino acid changes in the protein (A49P, A262V, and V296I) with the amino acid combination PAV identifying the taster variant (and AVI identifying the non-taster variant).

Gene Name: taste receptor, type 2, member 38
Synonyms: TAS2R38, Phenylthiocarbamide tasting, PTC bitter taste receptor, T2R61, PTC, T2R38
Target Sequences: NP_789787.4 P59533

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
TAS2R38 (3)
No (3)
Myc-DDK (Flag) (3)
Human (2)
293T Cells (1)
HEK 293 Cells (2)
TAS2R38 Protein - Purified recombinant protein TAS2R38 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
37.7 kDa
20 µg/$1,107
TAS2R38 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
37.7 kDa
100 µg/$494
TAS2R38 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
37.7 kDa
20 µg/$150
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).