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TAS2R14 / TRB1

taste receptor, type 2, member 14

Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.

Gene Name:	taste receptor, type 2, member 14
Family/Subfamily:	GPCR , Taste
Synonyms:	TAS2R14, T2R14, TRB1
Target Sequences:	NM_023922 NP_076411.1 Q9NYV8

Publications (2)

Flavones modulate respiratory epithelial innate immunity: Anti-inflammatory effects and activation of the T2R14 receptor. Hariri BM, McMahon DB, Chen B, Freund JR, Mansfield CJ, Doghramji LJ, Adappa ND, Palmer JN, Kennedy DW, Reed DR, Jiang P, Lee RJ. The Journal of biological chemistry. 2017 May;292:8484-8497. (Human) [Full Text Article] [PubMed:28373278] [PMC:PMC5437252] Related Antibodies: LS-C120957.

Cholesterol modulates the signaling of chemosensory bitter taste receptor T2R14 in human airway cells. Feroz Ahmed Shaik , Manoj Reddy Medapati , Prashen Chelikani. The Breast : official journal of the European Society of Mastology. 2019 Jan;316:L45-L57. [Full Text Article] [PubMed:30358435] Related Antibodies: LS-C120957.

TAS2R14 / TRB1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.

Human TAS2R14 / TRB1 Protein (Recombinant GST, N-terminus) (aa151-260) - LS-G62382

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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