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S100A4 / FSP1
S100 calcium binding protein A4
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
| Gene Name: | S100 calcium binding protein A4 |
| Synonyms: | S100A4, 42A, 18A2, Fibroblast-specific protein-1, FSP1, MTS1, PEL98, Protein Mts1, Calvasculin, CAPL, Metastasin, p9KA, Protein S100-A4 |
| Target Sequences: | NM_019554 NP_062427.1 P26447 |
Publications (3)
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