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CDK6

cyclin-dependent kinase 6

Serine/threonine-protein kinase involved in the control of the cell cycle and differentiation; promotes G1/S transition. Phosphorylates pRB/RB1 and NPM1. Interacts with D-type G1 cyclins during interphase at G1 to form a pRB/RB1 kinase and controls the entrance into the cell cycle. Involved in initiation and maintenance of cell cycle exit during cell differentiation; prevents cell proliferation and regulates negatively cell differentiation, but is required for the proliferation of specific cell types (e.g. erythroid and hematopoietic cells). Essential for cell proliferation within the dentate gyrus of the hippocampus and the subventricular zone of the lateral ventricles. Required during thymocyte development. Promotes the production of newborn neurons, probably by modulating G1 length. Promotes, at least in astrocytes, changes in patterns of gene expression, changes in the actin cytoskeleton including loss of stress fibers, and enhanced motility during cell differentiation. Prevents myeloid differentiation by interfering with RUNX1 and reducing its transcription transactivation activity, but promotes proliferation of normal myeloid progenitors. Delays senescence. Promotes the proliferation of beta-cells in pancreatic islets of Langerhans.

Gene Name: cyclin-dependent kinase 6
Family/Subfamily: Protein Kinase , CDC2/CDK
Synonyms: CDK6, CDKN6, Cell division protein kinase 6, Cyclin-dependent kinase 6, Crk2, PLSTIRE
Target Sequences: NM_001259 NP_001250.1 Q00534

☰ Filters
Antibodies (76)
Proteins (12)
ELISA Kits (8)
Over-Expression Lysate (4)
Primary (76)
Recombinant (8)
Sandwich (7)
Sandwich CLIA (1)
CDK6 (96)
Human (78)
Mouse (32)
Rat (26)
Bovine (7)
Chicken (4)
Chimpanzee (3)
Dog (7)
Gibbon (3)
Horse (7)
Monkey (4)
Pig (4)
Porcine (1)
Rabbit (8)
Zebrafish (1)
IHC (40)
IHC-Fr (9)
IHC-P (11)
WB (67)
ELISA (20)
ICC (3)
IF (14)
IP (21)
rabbit (52)
mouse (24)
Product Group
IHCPlus (3)
IgG (46)
IgG1 (22)
IgG1,k (1)
IgG2b,k (1)
monoclonal mc (24)
polyclonal pc (52)
8H4 (1)
DCS-130 (1)
DCS-83 (2)
DCS-83.1 (1)
IML-6 (3)
K6.83 (3)
K6.90 (2)
12 x 8-Well Microstrips (1)
96-Well Microplate (1)
96-Well Strip Plate (6)
AP Conjugated (3)
APC Conjugated (2)
Azide-free (3)
Biotin Conjugated (5)
FITC Conjugated (4)
HRP Conjugated (4)
Magnetic beads Conjugated (1)
PE Conjugated (3)
Preservative Free (1)
Sepharose Conjugated (1)
Unconjugated (53)
aa285-312 (8)
C-Terminus (4)
pTyr13 (4)
pTyr24 (4)
Tyr13 (1)
aa155-301 (1)
aa250-300 (1)
aa291-310 (1)
aa30-65 (1)
pTyr292 (1)
No (96)
Plasma (3)
Serum (3)
Tissue Homogenates (2)
GST (2)
GST, N-terminus (2)
Myc-DDK (Flag) (6)
Human (10)
293T Cells (2)
HEK 293 Cells (4)
Insect Cells (2)
Wheat Germ Extract (4)
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Biologically active (2)
CDK6 Antibody - Anti-CDK6 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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CDK6 Mouse anti-Human Monoclonal (8H4) Antibody
Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$440
CDK6 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$693
CDK6 Antibody - Immunohistochemistry of paraffin-embedded rat liver using CDK6 antibodyat dilution of 1:100 (40x lens).
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CDK6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IP, WB
Unconjugated
20 µl/$277; 50 µl/$319; 100 µl/$397; 200 µl/$499
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CDK6 Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
100 µg/$573
Select
CDK6 Mouse anti-Human Monoclonal (DCS-83) Antibody
Human
IHC, IP, WB
Unconjugated
5 ml/$401
CDK6 Antibody - Anti-CDK6 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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CDK6 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
CDK6 Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
CDK6 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
50 µl/$460
CDK6 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$776
Select
CDK6 Mouse anti-Human Monoclonal Antibody
Human
IHC, IP, WB
Unconjugated
100 µg/$421
CDK6 Antibody
Select
CDK6 Rabbit anti-Human Polyclonal (aa155-301) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$317
Select
CDK6 Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$622
Select
CDK6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$321
Select
CDK6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$321
Select
CDK6 Mouse anti-Human Monoclonal (Magnetic beads) (IML-6) Antibody
Mouse, Rat, Human
IP
Magnetic beads Conjugated
100 µg/$363
Select
CDK6 Mouse anti-Human Monoclonal (K6.83) Antibody
Mouse, Rat, Human
IF, IHC, IHC-Fr, IP, WB
Unconjugated
0.1 ml/$319; 0.5 ml/$532; 1 ml/$788
Select
CDK6 Mouse anti-Human Monoclonal (Biotin) (K6.83) Antibody
Mouse, Rat, Human
IF, IHC, IHC-Fr, IP, WB
Biotin Conjugated
0.1 ml/$361; 0.5 ml/$673; 1 ml/$875
Select
CDK6 Mouse anti-Human Monoclonal (Azide-free) (K6.83) Antibody
Mouse, Rat, Human
IF, IHC, IHC-Fr, IP, WB
Unconjugated, Azide-free
0.1 ml/$574; 0.2 ml/$819
Select
CDK6 Mouse anti-Human Monoclonal (K6.90) Antibody
Mouse, Rat, Human
IF, IHC, IHC-Fr, IP, WB
Unconjugated
0.1 ml/$319; 0.5 ml/$531; 1 ml/$787
Select
CDK6 Mouse anti-Human Monoclonal (Azide-free) (K6.90) Antibody
Mouse, Rat, Human
IF, IHC, IHC-Fr, IP, WB
Unconjugated, Azide-free
0.1 ml/$573; 0.2 ml/$819
Select
CDK6 Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
IF, IHC, IHC-Fr, WB
Unconjugated
100 µg/$631
CDK6 Antibody
Select
CDK6 Mouse anti-Human Monoclonal (DCS-130) Antibody
Mouse, Human
ICC, IHC, IHC-P, IP
Unconjugated
100 µg/$344
CDK6 Antibody - Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:200.
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CDK6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µl/$279; 100 µl/$309; 200 µl/$379
CDK6 Antibody - Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue.
Select
CDK6 Rabbit anti-Human Polyclonal (pTyr24) Antibody
IF, IHC, WB
Unconjugated
50 µl/$306; 100 µl/$381; 200 µl/$489
Select
CDK6 Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-Fr, IP, WB
Unconjugated
100 µg/$803
Select
CDK6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
60 µl/$278; 120 µl/$338; 200 µl/$440
Viewing 1-25 of 96 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).