CD83 is a member of the Ig superfamily. It contains an extracellular V-type domain, a single transmembrane domain and a 40 residue cytoplasmic tail. CD83 is used as a marker for mature, antigen presenting dendritic cells that are capable of generating tumor specific T cell immunity. CD83 is expressed by interfollicular interdigitating reticulum cells and more weakly by cells within germinal centers. It is also expressed by Langerhans cells in the skin, monocytes, macrophages, and activated dendritic cells.
|Gene Name:||CD83 molecule|
|Synonyms:||CD83, BL11, Cell surface protein HB15, CD83 antigen, CD83 molecule, Cell-surface glycoprotein, HCD83, B-cell activation protein, HB15|
|Target Sequences:||NM_004233 NP_004224.1 Q01151|
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