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CBR / CBR1

carbonyl reductase 1

NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.

Gene Name: carbonyl reductase 1
Synonyms: CBR1, Carbonyl reductase 1, Carbonyl reductase (NADPH) 1, HCBR1, Prostaglandin 9-ketoreductase, SDR21C1, Carbonyl reductase [NADPH] 1, CBR, CRN, Prostaglandin-E(2) 9-reductase
Target Sequences: NM_001757 NP_001748.1 P16152

☰ Filters
Antibodies (63)
Proteins (11)
ELISA Kits (5)
Custom (4)
Over-Expression Lysate (2)
Primary (63)
Recombinant (9)
Sandwich (1)
CBR / CBR1 (79)
Human (56)
Mouse (21)
Rat (20)
Bovine (5)
Chimpanzee (3)
Gibbon (3)
Hamster (4)
Monkey (1)
Orangutan (3)
Pig (5)
Rabbit (4)
IHC (12)
IHC-P (4)
WB (60)
Flo (1)
ELISA (13)
ICC (4)
IF (7)
IP (3)
Peptide-ELISA (2)
rabbit (52)
mouse (10)
goat (1)
Product Group
IHCPlus (3)
IgG (23)
IgG1 (4)
IgG2a,k (3)
monoclonal mc (9)
polyclonal pc (54)
2C9-B12-C4 (1)
4G11-1C7 (1)
AT2D6 (1)
AT4E12 (1)
OTI4B4 (2)
96-Well Strip Plate (5)
AP Conjugated (1)
APC (3)
APC Conjugated (4)
Biotin Conjugated (6)
Carrier-free (1)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (4)
Unconjugated (30)
aa2-271 (8)
aa2-277 (8)
aa66-271 (8)
aa107-156 (4)
aa227-277 (2)
150-230 aa, Internal (1)
Internal (1)
aa181-230 (1)
aa265-277 (1)
No (79)
Plasma (1)
Serum (1)
6His, N-terminus (1)
GST (1)
GST, N-terminus (1)
His (1)
His-T7 (3)
Myc-DDK (Flag) (3)
Human (8)
Mouse (1)
Rat (1)
293T Cells (1)
E. coli (6)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Yeast (1)
Purified (3)
CBR / CBR1 Antibody - Anti-CBR1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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CBR / CBR1 Mouse anti-Human Monoclonal (AT4E12) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$440
CBR / CBR1 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE), at 5 µg/ml.
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CBR / CBR1 Goat anti-Human Polyclonal (aa265-277) Antibody
Human
IF, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$460
CBR / CBR1 Antibody - Immunohistochemical analysis of CBR1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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CBR / CBR1 Rabbit anti-Human Polyclonal (Internal) Antibody
Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$289
CBR / CBR1 Antibody - Anti-CBR / CBR1 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
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CBR / CBR1 Rabbit anti-Human Polyclonal (aa181-230) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$515
CBR / CBR1 Antibody - 1:100 staining human prostate tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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CBR / CBR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
100 µl/$369; 200 µl/$411
CBR / CBR1 Antibody - ICC/IF analysis of CBR1 in HeLa cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human CBR1 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
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CBR / CBR1 Mouse anti-Human Monoclonal (AT2D6) Antibody
Human
ELISA, Flo, ICC, WB
Unconjugated
50 µl/$293; 100 µl/$355
CBR / CBR1 Protein
Select
Yeast
His
32.2 kD
500 µg/$1,000; 100 µg/$436; 20 µg/$326
CBR / CBR1 Protein
Select
E. coli
None
100 µg/$351; 500 µg/$694; 20 µg/$249
CBR / CBR1 Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-CBR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:2000)
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CBR / CBR1 Mouse anti-Human Monoclonal (OTI4B4) Antibody
Human
IHC, WB
Unconjugated
100 µl/$409
CBR / CBR1 Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-CBR1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:2000)
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CBR / CBR1 Mouse anti-Human Monoclonal (Carrier-free) (OTI4B4) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$473
CBR / CBR1 Antibody - Immunohistochemistry of paraffin-embedded Human breast cancer using CBR1 Polyclonal Antibody at dilution of 1:40.
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CBR / CBR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$242; 60 µl/$284; 120 µl/$343; 200 µl/$451
CBR / CBR1 Antibody - Immunohistochemistry of paraffin-embedded Human cervical cancer using CBR1 Polyclonal Antibody at dilution of 1:40.
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CBR / CBR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$242; 60 µl/$284; 120 µl/$343; 200 µl/$451
CBR / CBR1 Antibody - Immunofluorescence analysis of HeLa cells.
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CBR / CBR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$253; 50 µl/$279; 100 µl/$333; 200 µl/$429
CBR / CBR1 Antibody - Western blot of Carbonyl Reductase 1 antibody
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CBR / CBR1 Rabbit anti-Human Polyclonal (150-230 aa, Internal) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µl/$279; 100 µl/$309; 200 µl/$379
CBR / CBR1 Antibody - Immunofluorescent analysis of A549 cells using CBR1 Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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CBR / CBR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
50 µg/$284; 100 µg/$348
CBR / CBR1 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using CBR1 antibody.
Select
CBR / CBR1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$347
Select
CBR / CBR1 Mouse anti-Human Monoclonal (2C9-B12-C4) Antibody
Human
IF, WB
Unconjugated
100 µg/$439
Select
CBR / CBR1 Mouse anti-Human Monoclonal Antibody
Human
ICC, WB
Unconjugated
100 µl/$433
Select
CBR / CBR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
60 µl/$280; 120 µl/$343; 200 µl/$451
CBR / CBR1 Antibody - Immunocytochemistry stain of HeLa using CBR1 mouse monoclonal antibody (1:100).
Select
CBR / CBR1 Mouse anti-Human Monoclonal Antibody
Human
ICC, WB
Unconjugated
100 µl/$381
Select
CBR / CBR1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µl/$433
CBR / CBR1 Antibody - Detection limit for recombinant GST tagged CBR1 is approximately 1 ng/ml as a capture antibody.
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CBR / CBR1 Mouse anti-Human Monoclonal (4G11-1C7) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$413
CBR / CBR1 Antibody - Immunocytochemistry stain of Hela using CBR1 mouse mAb (1:100).
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CBR / CBR1 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
50 µl/$315; 100 µl/$383; 200 µl/$479
Select
CBR / CBR1 Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$622
CBR / CBR1 Antibody - Detection of human Carbonyl Reductase 1/CBR1 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-Carbonyl Reductase 1/CBR1 antibody used for WB at 0.1 µg/ml. Detection: Chemiluminescence with an exposure time of 3 seconds.
Select
CBR / CBR1 Rabbit anti-Human Polyclonal (aa227-277) Antibody
Human
IP, WB
Unconjugated
100 µl/$483
Viewing 1-25 of 79 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).