PLRG1 is a core component of the cell division cycle 5-like (CDC5L) complex. The CDC5L complex is part of the spliceosome and is required for pre-mRNA splicing. The encoded protein plays a critical role in alternative splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
|Gene Name:||pleiotropic regulator 1|
|Synonyms:||PLRG1, Cwc1, Pleiotropic regulator 1, PRPF46, PRL1, PRP46, TANGO4|
|Target Sequences:||NM_002669 NP_002660.1 O43660|
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