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CD48

CD48 molecule

CD48 is a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: CD48 molecule
Synonyms: CD48, BCM1, BCM1 surface antigen, BLAST, BLAST1, CD48 molecule, MEM-102, MCD48, SLAMF2, CD48 antigen, HCD48, Leukocyte antigen MEM-102, TCT.1
Target Sequences: NM_001778 NP_001769.2 P09326

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).